Lecture

Neuromodulation: Methods and Applications

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In course

NX-436: Advanced methods for human neuromodulation

Neuromodulation is an expending field especially in human translational neuroscience and neurotechnology. This course will introduce to different approaches / technologies for neuromodulation, their underlying mechanisms of action and application in humans ...

Description

This lecture covers the history and current methods of neuromodulation, including transcranial magnetic and electric stimulation, deep brain stimulation, vagal nerve stimulation, and spinal cord stimulation. It also discusses the use of light, drugs, and sound in engineering neural activity, as well as the challenges and opportunities in personalized neuromodulation and closed-loop systems, incorporating machine learning and artificial intelligence.

Instructor

Friedhelm Christoph Hummel

Expertise Stroke recovery Healthy Aging Motor Control Motor Learning Cognitive Control Neuroplasticity Non-invasive Brain Stimulation Structural and functional Neuroimaging Connectivity Postal Address Campus Biotech Defitech Chair of Clinical Neuroengineering Brain Mind Institute, SV Neuro X Institute, Swiss Federal Institute of Technology EPFL Campus Biotech Rm H4.3.132.084, 9, Chemin des Mines 1202 Geneva Teaching & PhD PhD Students Maria Ploumitsakou, Simona Losacco, Fabienne Windel, Andrea Protani, Sta

Official source

Related concepts (17)

Neurostimulation

Neurostimulation is the purposeful modulation of the nervous system's activity using invasive (e.g. microelectrodes) or non-invasive means (e.g. transcranial magnetic stimulation or transcranial electric stimulation, tES, such as tDCS or transcranial alternating current stimulation, tACS). Neurostimulation usually refers to the electromagnetic approaches to neuromodulation.

Spinal cord injury

A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function. Symptoms may include loss of muscle function, sensation, or autonomic function in the parts of the body served by the spinal cord below the level of the injury. Injury can occur at any level of the spinal cord and can be complete, with a total loss of sensation and muscle function at lower sacral segments, or incomplete, meaning some nervous signals are able to travel past the injured area of the cord up to the Sacral S4-5 spinal cord segments.

Spinal cord injury research

Spinal cord injury research seeks new ways to cure or treat spinal cord injury in order to lessen the debilitating effects of the injury in the short or long term. There is no cure for SCI, and current treatments are mostly focused on spinal cord injury rehabilitation and management of the secondary effects of the condition. Two major areas of research include neuroprotection, ways to prevent damage to cells caused by biological processes that take place in the body after the injury, and neuroregeneration, regrowing or replacing damaged neural circuits.

Closed-loop controller

A closed-loop controller or feedback controller is a control loop which incorporates feedback, in contrast to an open-loop controller or non-feedback controller. A closed-loop controller uses feedback to control states or outputs of a dynamical system. Its name comes from the information path in the system: process inputs (e.g., voltage applied to an electric motor) have an effect on the process outputs (e.g., speed or torque of the motor), which is measured with sensors and processed by the controller; the result (the control signal) is "fed back" as input to the process, closing the loop.

Closed-loop transfer function

In control theory, a closed-loop transfer function is a mathematical function describing the net result of the effects of a feedback control loop on the input signal to the plant under control. The closed-loop transfer function is measured at the output. The output signal can be calculated from the closed-loop transfer function and the input signal. Signals may be waveforms, , or other types of data streams.

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