Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Home

Lecture

SOD1 Pathology: Mechanisms and Implications

About
Privacy
Disclaimer

Graph Chatbot

Related lectures (32)

Protein Aggregation Mechanisms: C. elegans Model Insights

Delves into protein aggregation mechanisms using C. elegans, covering misfolding, aggregation pathways, kinetics, chaperones, and stochastic nucleation.

Protein Folding: Chaperone Solutions

Explores chaperones' role in guiding protein folding and preventing misfolding through the functional cycle of Hsp70 and the DnaK chaperone system.

The Molecular Interactions that Shape Tau Polymorphs

Explores the molecular interactions shaping tau polymorphs and the role of Hsp40s in regulating tau aggregation.

Cytoskeleton: Actin Filaments and Microtubules

Explores actin filaments, microtubules, monomers, proteins, dimer formation, and protein aggregation in the cytoskeleton.

Mitochondrial Protein Import: Challenges and Mechanisms

Delves into challenges and mechanisms of mitochondrial protein import, focusing on precursor accumulation and protein folding.

Hsp70 Chaperone Binding: Substrate Selectivity and Function

Explores the selective promiscuity in binding of the E. coli Hsp70 chaperone to unfolded or misfolded protein substrates, examining its implications in protein folding mechanisms.

Protein Aggregation and Disaggregation: Insights from In Vivo Studies

Explores protein aggregation and disaggregation mechanisms, focusing on huntingtin protein in Huntington's Disease.

Parkinson's Disease Alpha-Synuclein: Amyloid Formation and Cross-reactivity

Explores Parkinson's alpha-synuclein cross-reactivity, amyloid formation, compound impact, and copper chaperones.

Cellular Heat Shock Response: Rethinking the Significance

Delves into the cellular heat shock response, emphasizing the absence of a sensor mechanism and the restoration of misfolded protein aggregates.

Molecular Chaperone Action: Small Heat Shock Proteins

Explores the molecular chaperone action of small heat shock proteins in proteostasis, focusing on their interaction with misfolded proteins and amyloid fibrils.

Proteostasis Regulation: Chaperone Interactions and Post-Translational Modifications

Explores proteostasis regulation through chaperone interactions and post-translational modifications, revealing insights into protein quality control mechanisms.

Protein Fibrillar Aggregation Log in to Mediaspace to watch this video

Explores cryo-EM techniques for studying protein aggregation in neurodegenerative diseases, focusing on a-synuclein.

Page 2 of 2