Orphan drugAn orphan drug is a pharmaceutical agent that is developed to treat certain rare medical conditions. An orphan drug would not be profitable to produce without government assistance, due to the small population of patients affected by the conditions. The conditions that orphan drugs are used to treat are referred to as orphan diseases. The assignment of orphan status to a disease and to drugs developed to treat it is a matter of public policy that depends on the legislation (if there is any) of the country.
Approved drugAn approved drug is a medicinal preparation that has been validated for a therapeutic use by a ruling authority of a government. This process is usually specific by country, unless specified otherwise. In the United States, the FDA approves drugs. Before a drug can be prescribed, it must undergo the FDA's approval process. While a drug can feasibly be used off-label (for non-approved indications), it still is required to be approved for a specific disease or medical condition.
Box plotIn descriptive statistics, a box plot or boxplot is a method for graphically demonstrating the locality, spread and skewness groups of numerical data through their quartiles. In addition to the box on a box plot, there can be lines (which are called whiskers) extending from the box indicating variability outside the upper and lower quartiles, thus, the plot is also called the box-and-whisker plot and the box-and-whisker diagram. Outliers that differ significantly from the rest of the dataset may be plotted as individual points beyond the whiskers on the box-plot.
Astronomical objectAn astronomical object, celestial object, stellar object or heavenly body is a naturally occurring physical entity, association, or structure that exists within the observable universe. In astronomy, the terms object and body are often used interchangeably. However, an astronomical body or celestial body is a single, tightly bound, contiguous entity, while an astronomical or celestial object is a complex, less cohesively bound structure, which may consist of multiple bodies or even other objects with substructures.
Causal inferenceCausal inference is the process of determining the independent, actual effect of a particular phenomenon that is a component of a larger system. The main difference between causal inference and inference of association is that causal inference analyzes the response of an effect variable when a cause of the effect variable is changed. The science of why things occur is called etiology, and can be described using the language of scientific causal notation. Causal inference is said to provide the evidence of causality theorized by causal reasoning.
Public participationPublic participation, also known as citizen participation or patient and public involvement, is the inclusion of the public in the activities of any organization or project. Public participation is similar to but more inclusive than stakeholder engagement. Generally public participation seeks and facilitates the involvement of those potentially affected by or interested in a decision. This can be in relation to individuals, governments, institutions, companies or any other entities that affect public interests.
Public participation (decision making)Citizen Participation or Public Participation in social science refers to different mechanisms for the public to express opinions—and ideally exert influence—regarding political, economic, management or other social decisions. Participatory decision-making can take place along any realm of human social activity, including economic (i.e. participatory economics), political (i.e. participatory democracy or parpolity), management (i.e. participatory management), cultural (i.e. polyculturalism) or familial (i.
Near-Earth objectA near-Earth object (NEO) is any small Solar System body whose orbit brings it into proximity with Earth. By convention, a Solar System body is a NEO if its closest approach to the Sun (perihelion) is less than 1.3 astronomical units (AU). If a NEO's orbit crosses the Earth's orbit, and the object is larger than across, it is considered a potentially hazardous object (PHO). Most known PHOs and NEOs are asteroids, but a small fraction are comets. There are over 30,503 known near-Earth asteroids (NEAs) and over a hundred known short-period near-Earth comets (NECs).
