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This lecture covers the organization of the course, including class lectures, exercises, student seminars, and course evaluation. It delves into the grading policy, course topics such as bioelectricity, electrodes, signal processing, and implantable systems. The course goals encompass fundamental expertise, microelectronic-related expertise, technology-related expertise, and soft skills. It also discusses the material sources, additional information sources, and references related to implantable biomedical microsystems. Furthermore, it explores the use of CMOS ICs in biomedical instrumentation, societal shifts in biomedical engineering, common medical measurands, and the usage of biomedical systems. The lecture concludes with neural engineering definitions, bioimplantable microsystems, and specific examples like pacemakers.