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This lecture covers research on sustainable design of steel structures against natural hazards and wind energy systems. Prof. Dimitrios Lignos discusses the challenges in designing resilient structures, the impact of earthquakes, and the methodology for risk assessment. Prof. Fernando Porté-Agel presents the optimization of wind energy systems, focusing on wind farm layout and control strategies. The lecture also includes discussions on wind turbine wakes, wake prediction, and analytical modeling for wind farm power prediction. Ongoing research at the Wind Engineering and Renewable Energy Laboratory (WIRE) is highlighted, including alternative turbine designs and urban flow simulations.