Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Lecture

Nanomaterials in Tissue Engineering

Description

This lecture covers the use of micro- and nano-materials in tissue engineering, focusing on scaffold construction, fiber bonding techniques, solvent casting, and particulate leaching methods. It discusses the production of nanofiber scaffolds, control of mechanical properties, biodegradation, and rapid prototyping techniques. The lecture also explores the importance of scaffold materials, hydrogel properties, and the creation of tubular tissues with layered structures. Additionally, it delves into the enhancement of electrical properties in scaffolds through the use of nanoparticles and magnetic forces for cell alignment.

Official source

Related concepts (32)

Tissue engineering

Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues. Tissue engineering often involves the use of cells placed on tissue scaffolds in the formation of new viable tissue for a medical purpose but is not limited to applications involving cells and tissue scaffolds.

Nanoparticle

A nanoparticle or ultrafine particle is usually defined as a particle of matter that is between 1 and 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead.

Nanomaterials

Nanomaterials describe, in principle, materials of which a single unit is sized (in at least one dimension) between 1 and 100 nm (the usual definition of nanoscale). Nanomaterials research takes a materials science-based approach to nanotechnology, leveraging advances in materials metrology and synthesis which have been developed in support of microfabrication research. Materials with structure at the nanoscale often have unique optical, electronic, thermo-physical or mechanical properties.

Silver nanoparticle

Silver nanoparticles are nanoparticles of silver of between 1 nm and 100 nm in size. While frequently described as being 'silver' some are composed of a large percentage of silver oxide due to their large ratio of surface to bulk silver atoms. Numerous shapes of nanoparticles can be constructed depending on the application at hand. Commonly used silver nanoparticles are spherical, but diamond, octagonal, and thin sheets are also common. Their extremely large surface area permits the coordination of a vast number of ligands.

Hydrogel

A hydrogel is a biphasic material, a mixture of porous, permeable solids and at least 10% by weight or volume of interstitial fluid composed completely or mainly by water. In hydrogels the porous permeable solid is a water insoluble three dimensional network of natural or synthetic polymers and a fluid, having absorbed a large amount of water or biological fluids. These properties underpin several applications, especially in the biomedical area. Many hydrogels are synthetic, but some are derived from nature.

Related lectures (32)

Macro-materials for Tissue Engineering

Covers the use of macro-materials in tissue engineering, including key components, scaffold classification, bioresorbable polymers, and hydrogel applications.

Hydrogels as Biomaterials

Explores the definition, key properties, synthesis schemes, and applications of hydrogels as biomaterials, emphasizing their importance in drug delivery, tissue engineering, and cell biology.

Tissue Engineering Paradigm: Polymers and Biomaterials

Explores the tissue engineering paradigm, focusing on steps of cell isolation, seeding cells on a scaffold, cell stimulation in a bioreactor, and implantation of tissue engineered constructs.

Glass Transition: Polymer Properties

Explores glass and melting transitions in polymers, including characterization methods and specific polymer properties.

Immune Tissue Engineering: Mechanisms and Applications