A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled.
In probability theory, an experiment or trial (see below) is any procedure that can be infinitely repeated and has a well-defined set of possible outcomes, known as the sample space. An experiment is said to be random if it has more than one possible outcome, and deterministic if it has only one. A random experiment that has exactly two (mutually exclusive) possible outcomes is known as a Bernoulli trial. When an experiment is conducted, one (and only one) outcome results— although this outcome may be included in any number of events, all of which would be said to have occurred on that trial.
A sample-return mission is a spacecraft mission to collect and return samples from an extraterrestrial location to Earth for analysis. Sample-return missions may bring back merely atoms and molecules or a deposit of complex compounds such as loose material and rocks. These samples may be obtained in a number of ways, such as soil and rock excavation or a collector array used for capturing particles of solar wind or cometary debris. Nonetheless, concerns have been raised that the return of such samples to planet Earth may endanger Earth itself.
A Mars sample-return (MSR) mission is a proposed mission to collect rock and dust samples on Mars and return them to Earth. Such a mission would allow more extensive analysis than that allowed by onboard sensors. The three most recent concepts are a NASA-ESA proposal, a CNSA proposal, Tianwen-3, and a Roscosmos proposal, Mars-Grunt. Although NASA and ESA's plans to return the samples to Earth are still in the design stage as of 2022, samples have been gathered on Mars by the Perseverance rover.
A sketch (ultimately from Greek σχέδιος – schedios, "done extempore") is a rapidly executed freehand drawing that is not usually intended as a finished work. A sketch may serve a number of purposes: it might record something that the artist sees, it might record or develop an idea for later use or it might be used as a quick way of graphically demonstrating an image, idea or principle. Sketching is the most inexpensive art medium. Sketches can be made in any drawing medium.