Lecture

Respiratory System Function: Ventilation and Circulation

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In course

BIO-377: Physiology by systems

Le but est de connaitre et comprendre le fonctionnement des systèmes cardiovasculaire, urinaire, respiratoire, digestif, ainsi que du métabolisme de base et sa régulation afin de déveloper une réflection scientifique biomédicale. ...

Description

This lecture covers the function of the respiratory system, focusing on the mechanics of ventilation and respiration. Topics include the role of inspiratory and expiratory muscles, the importance of intra-thoracic pressure variation, spirometry principles, lung volumes, respiratory muscle movements, lung compliance, pulmonary circulation, and the forces involved in alveolar fluid circulation. Additionally, it discusses the concepts of dead and functional lung spaces, the role of surfactant in reducing surface tension, and the dynamics of pulmonary arterial circulation. The lecture also explores the impact of lung volume changes, pressure gradients, and the effects of surfactant on pulmonary compliance.

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Instructor

Sylvain Roy

1995: Diplôme fédéral de médecin 2000: Thèse de doctorat en médecine 2001: Diplôme fédéral de spécialiste FMH en ophtalmologie et ophtalmochirurgie 2003: Diplôme d'étude spécialisée en ingénierie biomédicale

Official source

Ontological neighbourhood

Health sciences

Pulmonology: Respiratory disease

Intensive care medicine: Topics in intensive care medicine

Related concepts (32)

Muscles of respiration

The muscles of respiration are the muscles that contribute to inhalation and exhalation, by aiding in the expansion and contraction of the thoracic cavity. The diaphragm and, to a lesser extent, the intercostal muscles drive respiration during quiet breathing. The elasticity of these muscles is crucial to the health of the respiratory system and to maximize its functional capabilities. Thoracic diaphragm The diaphragm is the major muscle responsible for breathing.

Spirometry

Spirometry (meaning the measuring of breath) is the most common of the pulmonary function tests (PFTs). It measures lung function, specifically the amount (volume) and/or speed (flow) of air that can be inhaled and exhaled. Spirometry is helpful in assessing breathing patterns that identify conditions such as asthma, pulmonary fibrosis, cystic fibrosis, and COPD. It is also helpful as part of a system of health surveillance, in which breathing patterns are measured over time.

Lung

The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the air and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange.

Respiratory disease

Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, the nerves and muscles of respiration. Respiratory diseases range from mild and self-limiting, such as the common cold, influenza, and pharyngitis to life-threatening diseases such as bacterial pneumonia, pulmonary embolism, tuberculosis, acute asthma, lung cancer, and severe acute respiratory syndromes, such as COVID-19.

Lung compliance

Lung compliance, or pulmonary compliance, is a measure of the lung's ability to stretch and expand (distensibility of elastic tissue). In clinical practice it is separated into two different measurements, static compliance and dynamic compliance. Static lung compliance is the change in volume for any given applied pressure. Dynamic lung compliance is the compliance of the lung at any given time during actual movement of air. Low compliance indicates a stiff lung (one with high elastic recoil) and can be thought of as a thick balloon – this is the case often seen in fibrosis.

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