Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Lecture

Cyclic Peptides and Macrocycles

Related lectures (32)

Peptide Therapeutics

Explores the development and advantages of peptide therapeutics, including conversion into peptidomimetics and solid phase peptide synthesis.

DNA-Encoded Libraries

Explores DNA-encoded libraries for drug discovery, covering synthesis techniques, pros and cons, and diverse DEL methods.

Identifying Drug Targets with Thermal-Shift Profiling

Showcases correlations between different organs' thermal profiles to identify drug targets.

Small Molecule Drugs: Genetic Diseases

Delves into the molecular basis of genetic diseases, discussing specific examples like Phenylketonuria and Haemophilia A, and the development of small molecule drugs for genetic disorders.

Sustainable Adhesives: Innovations and Applications

Explores the history, advantages, and classification of adhesives, including sustainable options like natural adhesives and bioadhesives.

Protein Translocation in the Endoplasmic Reticulum

Explains protein translocation in the endoplasmic reticulum, focusing on signal peptides and co-translational transfer across the ER membrane.

Introduction: small molecule drugs for cancer

Introduces small molecule drugs for cancer treatment, covering drug discovery, mechanisms of action, and historical development of anti-cancer agents.

Antibodies: Basics and Early Development

Explores the basics and early development of antibodies, including their structure, function, diversity, and application in diseases.

Proteomics: Post-Translational Modifications and Interactions

Explores proteomics for post-translational modifications and protein interactions.

Protein-Ligand Interactions

Explores the principles of protein-ligand interactions, covering methods for measuring affinity and kinetics in drug development.

Deep Generative Models in Drug Discovery

Explores the application of deep generative models in drug discovery, focusing on designing small molecules and optimizing molecular structures.

Protein Composition and Structure

Explores protein composition, peptide bonds, secondary structures, and protein folding prediction.

Frontiers in Chemical Biology

Explores the druggable proteome, PROTACS strategy, ubiquitin attachment, and drug development paradigms.

Protein Aggregation Kinetics and Drug Discovery

Explores protein aggregation kinetics, drug discovery, and targeting oligomers in misfolding diseases.

Antibodies: Technologies and Therapeutics

Explores the development and challenges of antibody-based therapeutics, including chimeric and humanized antibodies, alternative scaffolds, and in vitro selection.

Infectious Diseases: Small Molecule Drugs

Explores small molecule drugs for infectious diseases, covering global mortality rates, viral and bacterial injuries, antiviral and antibacterial agents, and the development of COX2 inhibitors.

Precision Electrophile Signaling: Tools for Unconventional Codes

Presents T-REX, a method for studying electrophile signaling in vivo and its applications in live cells and animal models.

Small Molecule Drugs: Cardiovascular Diseases

Explores the molecular basis and treatment of cardiovascular diseases, focusing on atherosclerosis, hypertension, and drug therapies.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Interrogating SAR in Medical Chemistry Log in to Mediaspace to watch this video

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.