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Lecture

Electrical Neural Stimulation: Fundamentals & Applications

In course

EE-519: Bioelectronics and biomedical microelectronics

The course covers the fundaments of bioelectronics and integrated microelectronics for biomedical and implantable systems. Issues and trade-offs at the circuit and systems levels of invasive microelectronic systems as well as their eluding designs, methods ...

Description

This lecture covers the fundamentals of electrical neural stimulation, including types of stimulation methods, waveforms, and electrical circuits. It explores the physiological origin of neural stimulation, the electrode-tissue interface, and the electrochemistry of stimulation. The lecture delves into the concepts of charge balancing, electrode damage, tissue damage, and safe electrical levels for therapeutic stimulation. It also discusses the stimulation of excitable tissues such as brain, nerves, muscles, and the heart, highlighting the importance of balanced biphasic waveforms. Various stimulation waveforms and their implementations are compared, emphasizing the significance of charge-balanced biphasic stimulation for efficacy and safety.

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Instructor

Alexandre Schmid

Alexandre Schmid received the M.Sc. degree in microengineering and the Ph.D. degree in electrical engineering from the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, in 1994 and 2000, respectively. Since 1994, he has been with the EPFL, working with the Integrated Systems Laboratory as a Research and Teaching Assistant, and with the Electronics Laboratories as a Postdoctoral Fellow. In 2002, he was a Senior Research Associate with the Microelectronic Systems Laboratory, where he has been conducting research in the fields of bioelectronic interfaces and implantable biomedical electronics, nonconventional signal processing and neuromorphic hardware, and reliability of nanoelectronic devices, and also teaches with the Microengineering and Electrical Engineering Departments of EPFL. Since 2011, he is a Maître d'Enseignement et de Recherche (MER) Faculty Member with EPFL. He is a coauthor of two books, Reliability of Nanoscale Circuits and Systems, Methodologies and Circuit Architectures, Springer, 2011, and Wireless Cortical Implantable Systems, Springer, 2013, and a coeditor of one book, as well as over 100 articles published in journals and conferences. Dr. Schmid has served as the General Chair of the Fourth International Conference on Nano-Networks in 2009 and has been serving as an Associate Editor of the Institute of Electrical, Information, and Communication Engineers Electronics Express since 2009.

Official source

Ontological neighbourhood

Physics

Electromagnetism: Electrical networks

Chemistry

Physical chemistry: Electrochemistry

Related concepts (32)

Neurostimulation

Neurostimulation is the purposeful modulation of the nervous system's activity using invasive (e.g. microelectrodes) or non-invasive means (e.g. transcranial magnetic stimulation or transcranial electric stimulation, tES, such as tDCS or transcranial alternating current stimulation, tACS). Neurostimulation usually refers to the electromagnetic approaches to neuromodulation.

Equivalent circuit

In electrical engineering, an equivalent circuit refers to a theoretical circuit that retains all of the electrical characteristics of a given circuit. Often, an equivalent circuit is sought that simplifies calculation, and more broadly, that is a simplest form of a more complex circuit in order to aid analysis. In its most common form, an equivalent circuit is made up of linear, passive elements. However, more complex equivalent circuits are used that approximate the nonlinear behavior of the original circuit as well.

Electrical network

An electrical network is an interconnection of electrical components (e.g., batteries, resistors, inductors, capacitors, switches, transistors) or a model of such an interconnection, consisting of electrical elements (e.g., voltage sources, current sources, resistances, inductances, capacitances). An electrical circuit is a network consisting of a closed loop, giving a return path for the current. Thus all circuits are networks, but not all networks are circuits (although networks without a closed loop are often imprecisely referred to as "circuits").

LC circuit

File:LC parallel simple.svg|LC circuit diagram File:Low cost DCF77 receiver.jpg|LC circuit ''(left)'' consisting of ferrite coil and capacitor used as a tuned circuit in the receiver for a [[radio clock]] File:Tuned circuit of shortwave radio transmitter from 1938.jpg|Output tuned circuit of [[shortwave]] [[radio transmitter]] An LC circuit, also called a resonant circuit, tank circuit, or tuned circuit, is an electric circuit consisting of an inductor, represented by the letter L, and a capacitor, represented by the letter C, connected together.

Duality (electrical circuits)

In electrical engineering, electrical terms are associated into pairs called duals. A dual of a relationship is formed by interchanging voltage and current in an expression. The dual expression thus produced is of the same form, and the reason that the dual is always a valid statement can be traced to the duality of electricity and magnetism. Here is a partial list of electrical dualities: voltage – current parallel – serial (circuits) resistance – conductance voltage division – current division impedance – admittance capacitance – inductance reactance – susceptance short circuit – open circuit Kirchhoff's current law – Kirchhoff's voltage law.

Related lectures (50)

Neural Electrodes

Explores neural stimulation using electrodes, addressing challenges in charge injection and safe stimulation limits.

Neural Electrodes: Stimulation and Safety

Explores neural stimulation with electrodes, discussing current flow effects, charge injection challenges, and electrode material properties.

Electrical Resistance and Ohm's Law

Covers electrical resistance, Ohm's Law, conductor types, and power calculation in circuits.

Untitled

Transforming Sources: Voltage to Current