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This lecture covers the production and use of silica fume, an ultra-fine silicate by-product, in high-performance concrete, as well as the benefits of microfillerization. It also discusses the availability of supplementary cementitious materials like calcined clay, their ideal properties, and their role in ternary cements. The incorporation of fillers, such as limestone, to reduce porosity and enhance concrete properties is explained, along with examples of ternary cements like LC3. The lecture emphasizes the impact of these materials on concrete performance, including reduced heat output, lower density, and improved durability. Case studies, such as the Confederation Bridge in Canada and projects using calcined clay and limestone cement, demonstrate the practical applications and benefits of these innovative materials.