Lecture

Advanced Neuromodulation Methods

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

In course

NX-436: Advanced methods for human neuromodulation

Neuromodulation is an expending field especially in human translational neuroscience and neurotechnology. This course will introduce to different approaches / technologies for neuromodulation, their underlying mechanisms of action and application in humans ...

Description

This lecture covers advanced methods for human neuromodulation, focusing on transcranial electric stimulation and non-invasive deep brain stimulation. Topics include electrode placement, stimulation protocols, individualized MRI for accurate current delivery, optimization techniques, and home-based self-application challenges. The instructors discuss the potential of combining neuromodulation with behavioral training and other interventions, addressing issues such as heterogeneity in response, genetic factors, and external influences. They also explore the use of high-definition electrodes, current density optimization, and the application of techniques like tACS and deep TMS for modulating brain activity.

Instructor

Friedhelm Christoph Hummel

Expertise Stroke recovery Healthy Aging Motor Control Motor Learning Cognitive Control Neuroplasticity Non-invasive Brain Stimulation Structural and functional Neuroimaging Connectivity Postal Address Campus Biotech Defitech Chair of Clinical Neuroengineering Brain Mind Institute, SV Neuro X Institute, Swiss Federal Institute of Technology EPFL Campus Biotech Rm H4.3.132.084, 9, Chemin des Mines 1202 Geneva Teaching & PhD PhD Students Maria Ploumitsakou, Simona Losacco, Fabienne Windel, Andrea Protani, Sta

Official source

Related concepts (32)

Neurostimulation

Neurostimulation is the purposeful modulation of the nervous system's activity using invasive (e.g. microelectrodes) or non-invasive means (e.g. transcranial magnetic stimulation or transcranial electric stimulation, tES, such as tDCS or transcranial alternating current stimulation, tACS). Neurostimulation usually refers to the electromagnetic approaches to neuromodulation.

Neural coding

Neural coding (or neural representation) is a neuroscience field concerned with characterising the hypothetical relationship between the stimulus and the individual or ensemble neuronal responses and the relationship among the electrical activity of the neurons in the ensemble. Based on the theory that sensory and other information is represented in the brain by networks of neurons, it is thought that neurons can encode both digital and analog information.

Spike-timing-dependent plasticity

Spike-timing-dependent plasticity (STDP) is a biological process that adjusts the strength of connections between neurons in the brain. The process adjusts the connection strengths based on the relative timing of a particular neuron's output and input action potentials (or spikes). The STDP process partially explains the activity-dependent development of nervous systems, especially with regard to long-term potentiation and long-term depression.

Neural oscillation

Neural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons.

Transcranial direct-current stimulation

Transcranial direct current stimulation (tDCS) is a form of neuromodulation that uses constant, low direct current delivered via electrodes on the head. It was originally developed to help patients with brain injuries or neuropsychiatric conditions such as major depressive disorder. It can be contrasted with cranial electrotherapy stimulation, which generally uses alternating current the same way, as well as transcranial magnetic stimulation. Research shows increasing evidence for tDCS as a treatment for depression.

Related lectures (64)

Optimization of Neuroprosthetic Systems

Explores the optimization of neuroprosthetic systems, including sensory feedback restoration and neural stimulation strategies.

Synaptic Plasticity: Forms and Mechanisms

Explores different forms of synaptic plasticity and the mechanisms behind them, emphasizing the role of calcium in inducing and maintaining plastic changes.

Electrical Stimulation Circuit

Covers neurostimulation techniques and electrical stimulation circuits for neural stimulator chips.

Neuroplasticity and Brain Stimulation

Explores neuroplasticity, brain stimulation techniques, and their applications in various neuro-psychiatric disorders and motor learning.

Transcranial Magnetic Stimulation: Neuromodulation Insights