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Lecture

Physiopathology of Pain

In course

MICRO-568: Seminar in physiology and instrumentation

Acquérir la connaissance de l'état de l'art dans l'instrumentation bio-médicale. Comprendre la physiologie associée aux techniques de mesures. ...

Description

This lecture by the instructor covers the generality, definition, epidemiology, types, mechanisms, and pathways of pain, including the usefulness of pain, congenital analgesia, pain in evolution, nociception and pain in fish models, and chronic pain as a disease. It also discusses the prevalence, body locations, causes, sensitivity to pain, different types of pain (nociceptive, inflammatory, neuropathic), mechanisms of pain transmission, modulation, perception, the neuromatrix hypothesis, sensitization, control theories, and neuromodulation techniques.

Instructors (3)

Kamiar Aminian

Kamiar Aminian received the M.S. degree in electrical engineering in 1982, the Ph.D degree in biomedical engineering in 1989 and the Postgraduate degree on technical computing in 1993 from Ecole Polytechnique Fédérale de Lausanne (EPFL). He was assistant professor (1994-1996) with Sharif University of Technology (Tehran). He joint EPFL in 1996 where he is currently Professor of medical instrumentation and the director of the Laboratory of Movement Analysis and Measurement in the Institute of Bioengineering of EPFL. His research interests include methodologies for human movement monitoring and analysis in real world conditions mainly based on wearable technologies and inertial sensors with emphasis on gait, physical activity and sport. His research aims to perform outcome evaluation in orthopaedics, to improve motor function and intervention programs in aging and patients with movement disorders and pain, and to identify metrics of performance in sport science. Kamiar Aminian is a member of the International Society of Posture and Gait Research, the Institute of Electrical and Electronics Engineers, the European Society of Movement Analysis in Adults and Children, the Prevention of fall Network Europe, the Intentional Society of Biomechanics and the President of the 3D analysis of the human movement group. He is author or co-author of more than 450 scientific papers published in reviewed journals and presented at international conferences and holds 10 patents related to medical devices. Full CV ORCID

Philippe Renaud

Philippe Renaud is Professor at the Microsystem Laboratory (LMIS4) at EPFL. He is also the scientific director of the EPFL Center of MicroNanoTechnology (CMI). His main research area is related to micronano technologies in biomedical applications (BioMEMS) with emphasis on cell-chips, nanofluidics and bioelectronics. Ph. Renaud is invloved in many scientifics papers in his research area. He received his diploma in physics from the University of Neuchâtel (1983) and his Ph.D. degree from the University of Lausanne (1988). He was postdoctoral fellow at University of California, Berkeley (1988-89) and then at the IBM Zürich Research Laboratory in Switzerland (1990-91). In 1992, he joined the Sensors and Actuators group of the Swiss Center for Electronics and Microtechnology (CSEM) at Neuchâtel, Switzerland. He was appointed assistant professor at EPFL in 1994 and full professor in 1997. In summer 1996, he was visiting professor at the Tohoku University, Japan. Ph. Renaud is active in several scientific committee (scientific journals, international conferences, scientific advisory boards of companies, PhD thesis committee). He is also co-founder of the Nanotech-Montreux conference. Ph. Renaud is committed to valorization of basic research through his involvement in several high-tech start-up companies.

Official source

Ontological neighbourhood

Biology

Anatomy: Neuroanatomy

Related concepts (32)

Pain

Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Pain motivates organisms to withdraw from damaging situations, to protect a damaged body part while it heals, and to avoid similar experiences in the future.

Chronic pain

Chronic pain is classified as pain that lasts longer than three months. In medicine, the distinction between acute and chronic pain is sometimes determined by the amount of time since onset. Two commonly used markers are pain that continues at three months and six months since onset, but some theorists and researchers have placed the transition from acute to chronic pain at twelve months. Others apply the term acute to pain that lasts less than 30 days, chronic to pain of more than six months duration, and subacute to pain that lasts from one to six months.

Pain management

Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging. Most physicians and other health professionals provide some pain control in the normal course of their practice, and for the more complex instances of pain, they also call on additional help from a specific medical specialty devoted to pain, which is called pain medicine.

Back pain

Back pain is pain felt in the back. It may be classified as neck pain (cervical), middle back pain (thoracic), lower back pain (lumbar) or coccydynia (tailbone or sacral pain) based on the segment affected. The lumbar area is the most common area affected. An episode of back pain may be acute, subacute or chronic depending on the duration. The pain may be characterized as a dull ache, shooting or piercing pain or a burning sensation. Discomfort can radiate to the arms and hands as well as the legs or feet, and may include numbness or weakness in the legs and arms.

Nociception

Nociception (also nocioception, from Latin nocere to harm or hurt) is the sensory nervous system's process of encoding noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal to trigger an appropriate defensive response. In nociception, intense chemical (e.g., capsaicin present in chili pepper or cayenne pepper), mechanical (e.g.

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