Lecture

Analyzing Excitability: Force and Stimulus in Muscle Contraction

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In courses (2)

BIO-378: Physiology lab I

Le TP de physiologie introduit les approches expérimentales du domaine biomédical, avec les montages de mesure, les capteurs, le conditionnement des signaux, l'acquisition et traitement de données. Les résultats physiologiques finaux illustrent le contenu ...

BIO-379: Physiology lab II

Description

This lecture delves into the analysis of excitability in muscle contraction, focusing on the relationship between force and stimulus. The instructor explains how force measurement is influenced by factors like sensor mounting, crosstalk, and sensor movement. The lecture covers the impact of force on muscle deformation, the interference between sensors, and the importance of limiting crosstalk. Various configurations for force and position measurements are discussed, emphasizing the need to minimize interferences. Additionally, the lecture explores the role of the guide lever in force measurement and the challenges of accurately measuring force and position simultaneously.

Instructor

André Pexieder

Teaching & PhD Courses Physiology lab I BIO-378 The physiology laboratory introduce the experimental methods in the biomedical field, including experimental set-ups, transducers, signal conditioning, data acquisition and processing.The physiological end results illustrate the contents of the Physiologie par systèmes course. Physiology lab II BIO-379 The physiology laboratory introduce the experimental methods in the biomedical field, including experimental set-ups, transducer

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Related concepts (22)

Muscle contraction

Muscle contraction is the activation of tension-generating sites within muscle cells. In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. The termination of muscle contraction is followed by muscle relaxation, which is a return of the muscle fibers to their low tension-generating state.

Muscle cell

A muscle cell is also known as a myocyte when referring to either a cardiac muscle cell (cardiomyocyte) or a smooth muscle cell, as these are both small cells. A skeletal muscle cell is long and threadlike with many nuclei and is called a muscle fiber. Muscle cells (including myocytes and muscle fibers) develop from embryonic precursor cells called myoblasts. Myoblasts fuse from multinucleated skeletal muscle cells known as syncytia in a process known as myogenesis.

Muscle

Muscle is a soft tissue, one of the animal tissues that makes up the three different types of muscle. Muscle tissue gives skeletal muscles the ability to contract. Muscle is formed during embryonic development, in a process known as myogenesis. Muscle tissue contains special contractile proteins called actin and myosin which interact to cause movement. Among many other muscle proteins present are two regulatory proteins, troponin and tropomyosin. Muscle tissue varies with function and location in the body.

Smooth muscle

Smooth muscle is an involuntary non-striated muscle, so-called because it has no sarcomeres and therefore no striations (bands or stripes). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit muscle, the whole bundle or sheet of smooth muscle cells contracts as a syncytium. Smooth muscle is found in the walls of hollow organs, including the stomach, intestines, bladder and uterus. In the walls of blood vessels, and lymph vessels, (excluding blood and lymph capillaries) it is known as vascular smooth muscle.

Striated muscle tissue

Striated muscle tissue is a muscle tissue that features repeating functional units called sarcomeres. The presence of sarcomeres manifests as a series of bands visible along the muscle fibers, which is responsible for the striated appearance observed in microscopic images of this tissue. There are two types of striated muscle: Cardiac muscle (heart muscle) Skeletal muscle (muscle attached to the skeleton) Striated muscle tissue contains T-tubules which enables the release of calcium ions from the sarcoplasmic reticulum.

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