Lectures related to Cryo-EM and Parkinson's Disease

Protein Aggregation in Neurodegenerative Diseases

Explores protein aggregation in neurodegenerative diseases, emphasizing the need to rethink treatment strategies and understand the role of post-translational modifications.

Protein self-assembly and phase transitions

Delves into protein self-assembly, phase transitions, and aggregation mechanisms in diseases like Alzheimer's.

Protein Structure and Function: Folding and Degradation

Covers protein folding, maturation, degradation, and the implications of misfolding in neurodegenerative diseases.

Protein Structure Determination: NMR Insights

Explores NMR spectroscopy for protein structure determination and introduces Cryo-EM as a complementary technique with recent advancements.

Plasma Membrane Structure and Proteins

Covers plasma membrane structure, protein composition, fatty acid variations, protein folding, and amino acid properties.

Protein Structure Determination

Explores protein structure determination using NMR and Cryo-EM techniques, covering chemical shifts, isotope labeling, NOE, and high-resolution imaging methods.

Parkinson's Disease Alpha-Synuclein: Amyloid Formation and Cross-reactivity

Explores Parkinson's alpha-synuclein cross-reactivity, amyloid formation, compound impact, and copper chaperones.

Parkinson's Disease: Genetic Factors

Explores genetic factors in Parkinson's disease, focusing on a-synuclein, Parkin, and PINK1, and their impact on mitochondrial quality control.

Proteins: Structure and Function

Explores the structure and function of proteins, emphasizing their diverse roles in living organisms.

Protein Folding: Mechanisms and Consequences

Explores protein folding, misfolding consequences, chaperones' role, and ATP importance.

The Molecular Interactions that Shape Tau Polymorphs

Explores the molecular interactions shaping tau polymorphs and the role of Hsp40s in regulating tau aggregation.

Cytoskeleton: Actin Filaments and Microtubules

Explores actin filaments, microtubules, monomers, proteins, dimer formation, and protein aggregation in the cytoskeleton.

Protein Structure: General Principles

Explores protein structures, folding principles, and sequence determinants, emphasizing the diverse three-dimensional structures proteins can adopt.

Protein Structure: General Principles

Discusses the organization of protein structures and the role of protein folding.

Intrinsically Disordered Proteins: Phase Separation and Membrane Interactions

Explores the behavior of intrinsically disordered proteins, polymer phase separation, Flory-Huggins theory, and biomolecular condensates.

Protein Composition and Structure

Explores protein composition, peptide bonds, structures, folding, and stability.

Polyglutamine Protein Aggregation: Molecular Structure and Pathogenic Mechanisms

Explores beta-hairpins in polyglutamine protein aggregation, focusing on Huntington's disease and the molecular mechanisms behind toxic fibril formation.

Electron Microscopy: Applications in Life Sciences

Explores Cryo-Electron Microscopy principles, workflows, resolution revolution, applications in life sciences, and microfluidics.

Protein Composition and Structure

Explores protein composition, peptide bonds, secondary structures, and protein folding prediction.

Protein Interaction Fingerprinting with Geometric Deep Learning

Explores deciphering protein interaction fingerprints using geometric deep learning and the challenges in computational protein-protein interaction design.