Lecture

Nanotoxicology: Emerging Discipline from Ultrafine Particles

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In course

ENV-400: Air pollution and climate change

A survey course describing the origins of air pollution and climate change ...

Description

This lecture explores nanotoxicology as a growing field originating from studies on ultrafine particles, focusing on the deposition, translocation, and effects of nanoparticles in the human body. It delves into the mechanisms of particle clearance, dissolution, and distribution in different regions of the respiratory system. The presentation also covers the emission, transformation, and impact of various compounds in Earth's atmosphere, emphasizing the role of oxidants, biogenic and anthropogenic sources, and their effects on ecosystems. Additionally, it discusses the concept of acid deposition, its mechanisms, impacts on aquatic and terrestrial environments, and the role of different chemical reactions in atmospheric processes.

Instructors (2)

Satoshi Takahama

Curriculum Vitae (pdf)

Julia Schmale

Expertise atmospheric science, aerosol-cloud interactions, climate change in polar regions Mission Extreme environments are particularly sensitive to climate change and are transforming at accelerated rates. This can have important global repercussions. EERL aims to create integrated process understanding by investigating interactions between the atmosphere, cryosphere, biosphere, ocean, land and anthroposphere. The goal is to characterize climate-change relevant and vertically-resolved processes that are d

Official source

Related concepts (32)

Respiratory system

The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies greatly, depending on the size of the organism, the environment in which it lives and its evolutionary history. In land animals the respiratory surface is internalized as linings of the lungs. Gas exchange in the lungs occurs in millions of small air sacs; in mammals and reptiles these are called alveoli, and in birds they are known as atria.

Air pollution

Air pollution is the contamination of air due to the presence of substances in the atmosphere that are harmful to the health of humans and other living beings, or cause damage to the climate or to materials. It is also the contamination of indoor or outdoor surrounding either by chemical activities, physical or biological agents that alters the natural features of the atmosphere. There are many different types of air pollutants, such as gases (including ammonia, carbon monoxide, sulfur dioxide, nitrous oxides, methane and chlorofluorocarbons), particulates (both organic and inorganic), and biological molecules.

Nanoparticle

A nanoparticle or ultrafine particle is usually defined as a particle of matter that is between 1 and 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead.

Respiratory tract

The respiratory tract is the subdivision of the respiratory system involved with the process of respiration in mammals. The respiratory tract is lined with respiratory epithelium as respiratory mucosa. Air is breathed in through the nose to the nasal cavity, where a layer of nasal mucosa acts as a filter and traps pollutants and other harmful substances found in the air. Next, air moves into the pharynx, a passage that contains the intersection between the oesophagus and the larynx.

Respiratory disease

Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, the nerves and muscles of respiration. Respiratory diseases range from mild and self-limiting, such as the common cold, influenza, and pharyngitis to life-threatening diseases such as bacterial pneumonia, pulmonary embolism, tuberculosis, acute asthma, lung cancer, and severe acute respiratory syndromes, such as COVID-19.

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