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This lecture covers the calculation of impact scores at the problem level, evaluating life cycle impacts using the Impact World+ framework. It discusses impact categories, indicators, and the calculation of impact scores based on midpoint level indicators. The lecture also delves into impact categories oriented towards problems, such as short-term climate change, ozone layer depletion, and aquatic acidification. Additionally, it explains the characterization factors for different substances, the inventory of life cycle impacts, and the relative contribution to impact scores. The process involves converting inventory flows into common units, aggregating them within impact categories, and assessing their potential contribution to different impact categories.