Lecture

Implant Size Impact on Foreign Body Reaction

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In course

NX-422: Neural interfaces

Neural interfaces (NI) are bioelectronic systems that interface the nervous system to digital technologies. This course presents their main building blocks (transducers, instrumentation & communication), reviews current and upcoming materials and technolog ...

Description

This lecture covers the impact of implant size on foreign body reaction, focusing on the use of polyimide-based flexible intracortical devices of different widths and thicknesses. Topics include tissue clearing for 3D molecular and optical interrogation, electrode impedance and glial consolidation, and histological analysis of stab wounds and lesioned cavities.

Instructors (2)

Mahsa Shoaran

Stéphanie Lacour

Stéphanie P. Lacour holds the Bertarelli Foundation Chair in Neuroprosthetic Technology in the School of Engineering at EPFL and leads the Laboratory for Soft Bioelectronic Interfaces. She received her PhD in Electrical Engineering from INSA de Lyon, France, and completed postdoctoral research at Princeton University and the University of Cambridge. She is the recipient of the 2006 MIT TR35, a University Research Fellowship of the Royal Society, European Research Council ERC Starting and POC Grants, and a SNSF-ERC Consolidator Grant. She was elected a 2015 Young Global Leader by the World Economic Forum.

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