Cell cycle checkpointCell cycle checkpoints are control mechanisms in the eukaryotic cell cycle which ensure its proper progression. Each checkpoint serves as a potential termination point along the cell cycle, during which the conditions of the cell are assessed, with progression through the various phases of the cell cycle occurring only when favorable conditions are met. There are many checkpoints in the cell cycle, but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint.
Calculus of constructionsIn mathematical logic and computer science, the calculus of constructions (CoC) is a type theory created by Thierry Coquand. It can serve as both a typed programming language and as constructive foundation for mathematics. For this second reason, the CoC and its variants have been the basis for Coq and other proof assistants. Some of its variants include the calculus of inductive constructions (which adds inductive types), the calculus of (co)inductive constructions (which adds coinduction), and the predicative calculus of inductive constructions (which removes some impredicativity).
Evaluation strategyIn a programming language, an evaluation strategy is a set of rules for evaluating expressions. The term is often used to refer to the more specific notion of a parameter-passing strategy that defines the kind of value that is passed to the function for each parameter (the binding strategy) and whether to evaluate the parameters of a function call, and if so in what order (the evaluation order). The notion of reduction strategy is distinct, although some authors conflate the two terms and the definition of each term is not widely agreed upon.
Spindle checkpointThe spindle checkpoint, also known as the metaphase-to-anaphase transition, the spindle assembly checkpoint (SAC), the metaphase checkpoint, or the mitotic checkpoint, is a cell cycle checkpoint during mitosis or meiosis that prevents the separation of the duplicated chromosomes (anaphase) until each chromosome is properly attached to the spindle. To achieve proper segregation, the two kinetochores on the sister chromatids must be attached to opposite spindle poles (bipolar orientation).
PrologProlog is a logic programming language associated with artificial intelligence and computational linguistics. Prolog has its roots in first-order logic, a formal logic, and unlike many other programming languages, Prolog is intended primarily as a declarative programming language: the program logic is expressed in terms of relations, represented as facts and rules. A computation is initiated by running a query over these relations.
Proof (truth)A proof is sufficient evidence or a sufficient argument for the truth of a proposition. The concept applies in a variety of disciplines, with both the nature of the evidence or justification and the criteria for sufficiency being area-dependent. In the area of oral and written communication such as conversation, dialog, rhetoric, etc., a proof is a persuasive perlocutionary speech act, which demonstrates the truth of a proposition.
Julia (programming language)Julia is a high-level, general-purpose dynamic programming language. Its features are well suited for numerical analysis and computational science. Distinctive aspects of Julia's design include a type system with parametric polymorphism in a dynamic programming language; with multiple dispatch as its core programming paradigm. Julia supports concurrent, (composable) parallel and distributed computing (with or without using MPI or the built-in corresponding to "OpenMP-style" threads), and direct calling of C and Fortran libraries without glue code.
Lambda calculusLambda calculus (also written as λ-calculus) is a formal system in mathematical logic for expressing computation based on function abstraction and application using variable binding and substitution. It is a universal model of computation that can be used to simulate any Turing machine. It was introduced by the mathematician Alonzo Church in the 1930s as part of his research into the foundations of mathematics. Lambda calculus consists of constructing lambda terms and performing reduction operations on them.
Lean (proof assistant)Lean is a theorem prover and programming language. It is based on the calculus of constructions with inductive types. The Lean project is an open-source project hosted on GitHub. It was launched by Leonardo de Moura at Microsoft Research in 2013. Lean has an interface, implemented as a Visual Studio Code extension and Language Server Protocol server, that differentiates it from other interactive theorem provers. It has native support for Unicode symbols, which can be typed using LaTeX-like sequences, such as "\times" for "×".
Semantics (computer science)In programming language theory, semantics is the rigorous mathematical study of the meaning of programming languages. Semantics assigns computational meaning to valid strings in a programming language syntax. It is closely related to, and often crosses over with, the semantics of mathematical proofs. Semantics describes the processes a computer follows when executing a program in that specific language. This can be shown by describing the relationship between the input and output of a program, or an explanation of how the program will be executed on a certain platform, hence creating a model of computation.
Lazy evaluationIn programming language theory, lazy evaluation, or call-by-need, is an evaluation strategy which delays the evaluation of an expression until its value is needed (non-strict evaluation) and which also avoids repeated evaluations (by the use of sharing). The benefits of lazy evaluation include: The ability to define control flow (structures) as abstractions instead of primitives. The ability to define potentially infinite data structures. This allows for more straightforward implementation of some algorithms.
SPSSSPSS Statistics is a statistical software suite developed by IBM for data management, advanced analytics, multivariate analysis, business intelligence, and criminal investigation. Long produced by SPSS Inc., it was acquired by IBM in 2009. Versions of the software released since 2015 have the brand name IBM SPSS Statistics. The software name originally stood for Statistical Package for the Social Sciences (SPSS), reflecting the original market, then later changed to Statistical Product and Service Solutions.