Lecture

Cortex-Wide Opto-Electrophysiological Recordings: eSee-Shells

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Description

This lecture discusses the development of 'eSee-Shells', chronic multimodal neural interface devices using transparent, inkjet-printed electrocorticography (ECoG) arrays. The speaker, Prof. Sarah Swisher, presents the benefits of flexible electronics for sensing neural activity across multiple brain regions. The talk covers the fabrication process of transparent electrode arrays, the simultaneous recording of ECoG and calcium imaging in awake mice, and the advantages of large-area implants for studying individual neurons and cortical networks. The lecture also explores the unique properties of the PEDOT:PSS interface, the impedance of electrode arrays, and the chronic durability of implanted eSee-Shells for over 100 days.

Official source

Related concepts (32)

Brain–computer interface

A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI) or smartbrain, is a direct communication pathway between the brain's electrical activity and an external device, most commonly a computer or robotic limb. BCIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions. They are often conceptualized as a human–machine interface that skips the intermediary component of the physical movement of body parts, although they also raise the possibility of the erasure of the discreteness of brain and machine.

Neural oscillation

Neural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons.

Neural engineering

Neural engineering (also known as neuroengineering) is a discipline within biomedical engineering that uses engineering techniques to understand, repair, replace, or enhance neural systems. Neural engineers are uniquely qualified to solve design problems at the interface of living neural tissue and non-living constructs (Hetling, 2008). The field of neural engineering draws on the fields of computational neuroscience, experimental neuroscience, neurology, electrical engineering and signal processing of living neural tissue, and encompasses elements from robotics, cybernetics, computer engineering, neural tissue engineering, materials science, and nanotechnology.

Brain implant

Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision.

Printed electronics

Printed electronics is a set of printing methods used to create electrical devices on various substrates. Printing typically uses common printing equipment suitable for defining patterns on material, such as screen printing, flexography, gravure, offset lithography, and inkjet. By electronic-industry standards, these are low-cost processes. Electrically functional electronic or optical inks are deposited on the substrate, creating active or passive devices, such as thin film transistors; capacitors; coils; resistors.

Related lectures (64)

Neural Signal Recording: Electrode Types and Applications

Explores various electrode types for neural signal recording and their applications in in-vivo and in-vitro settings.

Flexible Microelectrodes: Polymers & Applications

Covers polymer-based flexible microelectrodes, cuff electrodes, ECOG arrays, and peripheral nerve interfaces, discussing materials, properties, processing, and applications.

Miniaturized CMOS Interfaces

Explores miniaturized CMOS interfaces for neural recording and discusses spatial and temporal resolution, spike sorting, and wireless neural-interface-on-chip systems.