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This lecture provides an overview of the Swiss legislation on animal legal protection, focusing on the federal provisions and cantonal responsibilities. It covers topics such as the enforcement of animal welfare laws, the legal status of animals, and the ethical evaluation of animal experimentation. The lecture also discusses the roles and responsibilities of individuals involved in animal experimentation, the licensing procedures, and the principles of the 3Rs (Replace, Reduce, Refine) in animal research. Additionally, it explores the organization of animal experimentation at EPFL and in the Canton de Vaud, emphasizing the importance of minimizing harm to animals while maximizing benefits in scientific research.