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This lecture covers extrinsic noise sources in biomedical instrumentation, including interferences from electrical power lines, devices, and high-frequency signals. It also discusses artefacts like EMG and electrode movement, as well as noise reduction techniques such as shielding and impedance matching. The impact of capacitive coupling, skin-electrode impedance problems, and coupling with wires and devices are explained. Additionally, the lecture addresses the effects of magnetic fields on amplifiers in medical instrumentation.