Lecture

Continuous Culture: Chemostat

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In course

ChE-311: Biochemical engineering

This course introduces the basic principles of bioprocess engineering and highlights the similarities and differences with chemical engineering. Without going into the fundamentals, it proposes an overview of the techniques for fermentation as well as prod ...

Description

This lecture covers the principles and applications of continuous culture using a chemostat. It explains the design, operation, and advantages of chemostats in maintaining steady-state conditions for microbial growth. The lecture also delves into topics such as dilution rates, substrate and biomass concentration in steady-state, productivity comparisons with batch cultures, and the theory behind two-stage chemostats. Additionally, it discusses the determination of yield coefficients, maintenance energy, and the enhanced production in chemostats with cell recycle. The major applications of continuous culture reactors, deviations from ideal behavior, and the comparison between batch and continuous cultures are also explored.

Instructor

Simon Crelier

Teaching & PhD Courses Biochemical engineering ChE-311 This course introduces the basic principles of bioprocess engineering and highlights the similarities and differences with chemical engineering. Without going into the fundamentals, it proposes an overview of the techniques for fermentation as well as product purification (DownStream Processing) Bioprocesses and downstream processing ChE-437 This course aims at a more advanced coverage of the basic aspects discussed in m

Official source

Ontological neighbourhood

Energy engineering

Nuclear power: Topics in nuclear power

Related concepts (32)

Chemostat

A chemostat (from chemical environment is static) is a bioreactor to which fresh medium is continuously added, while culture liquid containing left over nutrients, metabolic end products and microorganisms is continuously removed at the same rate to keep the culture volume constant. By changing the rate with which medium is added to the bioreactor the specific growth rate of the microorganism can be easily controlled within limits.

Nuclear reactor

A nuclear reactor is a device used to initiate and control a fission nuclear chain reaction or nuclear fusion reactions. Nuclear reactors are used at nuclear power plants for electricity generation and in nuclear marine propulsion. Heat from nuclear fission is passed to a working fluid (water or gas), which in turn runs through steam turbines. These either drive a ship's propellers or turn electrical generators' shafts. Nuclear generated steam in principle can be used for industrial process heat or for district heating.

Deviation (statistics)

In mathematics and statistics, deviation is a measure of difference between the observed value of a variable and some other value, often that variable's mean. The sign of the deviation reports the direction of that difference (the deviation is positive when the observed value exceeds the reference value). The magnitude of the value indicates the size of the difference. Errors and residuals A deviation that is a difference between an observed value and the true value of a quantity of interest (where true value denotes the Expected Value, such as the population mean) is an error.

Light-water reactor

The light-water reactor (LWR) is a type of thermal-neutron reactor that uses normal water, as opposed to heavy water, as both its coolant and neutron moderator; furthermore a solid form of fissile elements is used as fuel. Thermal-neutron reactors are the most common type of nuclear reactor, and light-water reactors are the most common type of thermal-neutron reactor. There are three varieties of light-water reactors: the pressurized water reactor (PWR), the boiling water reactor (BWR), and (most designs of) the supercritical water reactor (SCWR).

Research reactor

Research reactors are nuclear fission-based nuclear reactors that serve primarily as a neutron source. They are also called non-power reactors, in contrast to power reactors that are used for electricity production, heat generation, or maritime propulsion. The neutrons produced by a research reactor are used for neutron scattering, non-destructive testing, analysis and testing of materials, production of radioisotopes, research and public outreach and education.

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