Cell junctionCell junctions or junctional complexes, are a class of cellular structures consisting of multiprotein complexes that provide contact or adhesion between neighboring cells or between a cell and the extracellular matrix in animals. They also maintain the paracellular barrier of epithelia and control paracellular transport. Cell junctions are especially abundant in epithelial tissues. Combined with cell adhesion molecules and extracellular matrix, cell junctions help hold animal cells together.
Homotopy categoryIn mathematics, the homotopy category is a built from the category of topological spaces which in a sense identifies two spaces that have the same shape. The phrase is in fact used for two different (but related) categories, as discussed below. More generally, instead of starting with the category of topological spaces, one may start with any and define its associated homotopy category, with a construction introduced by Quillen in 1967. In this way, homotopy theory can be applied to many other categories in geometry and algebra.
Homotopy colimit and limitIn mathematics, especially in algebraic topology, the homotopy limit and colimitpg 52 are variants of the notions of and colimit extended to the homotopy category . The main idea is this: if we have a diagramconsidered as an object in the , (where the homotopy equivalence of diagrams is considered pointwise), then the homotopy limit and colimits then correspond to the and coconewhich are objects in the homotopy category , where is the category with one object and one morphism.
Ring (mathematics)In mathematics, rings are algebraic structures that generalize fields: multiplication need not be commutative and multiplicative inverses need not exist. In other words, a ring is a set equipped with two binary operations satisfying properties analogous to those of addition and multiplication of integers. Ring elements may be numbers such as integers or complex numbers, but they may also be non-numerical objects such as polynomials, square matrices, functions, and power series.
Cell adhesionCell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released by cells into spaces between them. Cells adhesion occurs from the interactions between cell-adhesion molecules (CAMs), transmembrane proteins located on the cell surface.
Homotopy groupIn mathematics, homotopy groups are used in algebraic topology to classify topological spaces. The first and simplest homotopy group is the fundamental group, denoted which records information about loops in a space. Intuitively, homotopy groups record information about the basic shape, or holes, of a topological space. To define the n-th homotopy group, the base-point-preserving maps from an n-dimensional sphere (with base point) into a given space (with base point) are collected into equivalence classes, called homotopy classes.
Formal derivativeIn mathematics, the formal derivative is an operation on elements of a polynomial ring or a ring of formal power series that mimics the form of the derivative from calculus. Though they appear similar, the algebraic advantage of a formal derivative is that it does not rely on the notion of a limit, which is in general impossible to define for a ring. Many of the properties of the derivative are true of the formal derivative, but some, especially those that make numerical statements, are not.
Euclidean domainIn mathematics, more specifically in ring theory, a Euclidean domain (also called a Euclidean ring) is an integral domain that can be endowed with a Euclidean function which allows a suitable generalization of the Euclidean division of integers. This generalized Euclidean algorithm can be put to many of the same uses as Euclid's original algorithm in the ring of integers: in any Euclidean domain, one can apply the Euclidean algorithm to compute the greatest common divisor of any two elements.
Group (mathematics)In mathematics, a group is a non-empty set with an operation that satisfies the following constraints: the operation is associative, has an identity element, and every element of the set has an inverse element. Many mathematical structures are groups endowed with other properties. For example, the integers with the addition operation is an infinite group, which is generated by a single element called 1 (these properties characterize the integers in a unique way).
Model categoryIn mathematics, particularly in homotopy theory, a model category is a with distinguished classes of morphisms ('arrows') called 'weak equivalences', 'fibrations' and 'cofibrations' satisfying certain axioms relating them. These abstract from the category of topological spaces or of chain complexes ( theory). The concept was introduced by . In recent decades, the language of model categories has been used in some parts of algebraic K-theory and algebraic geometry, where homotopy-theoretic approaches led to deep results.
FibrationThe notion of a fibration generalizes the notion of a fiber bundle and plays an important role in algebraic topology, a branch of mathematics. Fibrations are used, for example, in Postnikov systems or obstruction theory. In this article, all mappings are continuous mappings between topological spaces. A mapping satisfies the homotopy lifting property for a space if: for every homotopy and for every mapping (also called lift) lifting (i.e. ) there exists a (not necessarily unique) homotopy lifting (i.e.
HomotopyIn topology, a branch of mathematics, two continuous functions from one topological space to another are called homotopic (from ὁμός "same, similar" and τόπος "place") if one can be "continuously deformed" into the other, such a deformation being called a homotopy (həˈmɒtəpiː, ; ˈhoʊmoʊˌtoʊpiː, ) between the two functions. A notable use of homotopy is the definition of homotopy groups and cohomotopy groups, important invariants in algebraic topology. In practice, there are technical difficulties in using homotopies with certain spaces.
Metric mapIn the mathematical theory of metric spaces, a metric map is a function between metric spaces that does not increase any distance. These maps are the morphisms in the , Met. Such functions are always continuous functions. They are also called Lipschitz functions with Lipschitz constant 1, nonexpansive maps, nonexpanding maps, weak contractions, or short maps. Specifically, suppose that and are metric spaces and is a function from to . Thus we have a metric map when, for any points and in , Here and denote the metrics on and respectively.
Puppe sequenceIn mathematics, the Puppe sequence is a construction of homotopy theory, so named after Dieter Puppe. It comes in two forms: a long exact sequence, built from the mapping fibre (a fibration), and a long coexact sequence, built from the mapping cone (which is a cofibration). Intuitively, the Puppe sequence allows us to think of homology theory as a functor that takes spaces to long-exact sequences of groups. It is also useful as a tool to build long exact sequences of relative homotopy groups.
Nowhere continuous functionIn mathematics, a nowhere continuous function, also called an everywhere discontinuous function, is a function that is not continuous at any point of its domain. If is a function from real numbers to real numbers, then is nowhere continuous if for each point there is some such that for every we can find a point such that and . Therefore, no matter how close we get to any fixed point, there are even closer points at which the function takes not-nearby values.
Homotopy lifting propertyIn mathematics, in particular in homotopy theory within algebraic topology, the homotopy lifting property (also known as an instance of the right lifting property or the covering homotopy axiom) is a technical condition on a continuous function from a topological space E to another one, B. It is designed to support the picture of E "above" B by allowing a homotopy taking place in B to be moved "upstairs" to E. For example, a covering map has a property of unique local lifting of paths to a given sheet; the uniqueness is because the fibers of a covering map are discrete spaces.
Étale fundamental groupThe étale or algebraic fundamental group is an analogue in algebraic geometry, for schemes, of the usual fundamental group of topological spaces. In algebraic topology, the fundamental group of a pointed topological space is defined as the group of homotopy classes of loops based at . This definition works well for spaces such as real and complex manifolds, but gives undesirable results for an algebraic variety with the Zariski topology.
Path space fibrationIn algebraic topology, the path space fibration over a based space is a fibration of the form where is the path space of X; i.e., equipped with the compact-open topology. is the fiber of over the base point of X; thus it is the loop space of X. The space consists of all maps from I to X that may not preserve the base points; it is called the free path space of X and the fibration given by, say, , is called the free path space fibration. The path space fibration can be understood to be dual to the mapping cone.
Simplicial complexIn mathematics, a simplicial complex is a set composed of points, line segments, triangles, and their n-dimensional counterparts (see illustration). Simplicial complexes should not be confused with the more abstract notion of a simplicial set appearing in modern simplicial homotopy theory. The purely combinatorial counterpart to a simplicial complex is an abstract simplicial complex. To distinguish a simplicial complex from an abstract simplicial complex, the former is often called a geometric simplicial complex.
Serre spectral sequenceIn mathematics, the Serre spectral sequence (sometimes Leray–Serre spectral sequence to acknowledge earlier work of Jean Leray in the Leray spectral sequence) is an important tool in algebraic topology. It expresses, in the language of homological algebra, the singular (co)homology of the total space X of a (Serre) fibration in terms of the (co)homology of the base space B and the fiber F. The result is due to Jean-Pierre Serre in his doctoral dissertation. Let be a Serre fibration of topological spaces, and let F be the (path-connected) fiber.
