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This lecture introduces Material and Energy Flow Analysis (MFA) for resource management. It covers the methodology, indicators, and advantages/disadvantages of Economy-wide MFA. The purpose of MFA includes early detection of harmful material accumulation, prediction of future quantities, and evaluation of policy effectiveness. The lecture discusses the flow types, indicators, and data sources for MFA. It also explores Circular Economy analysis, EW-MFA at a cantonal level, and the importance of data acquisition in MFA. The instructor presents case studies, system definitions, and the steps involved in MFA, emphasizing the significance of accurate data monitoring and interpretation.