Lectures related to Apoptosis: Regulation and Signaling

Cancer Biology: Base Excision Repair

Covers cancer biology topics on base excision repair, cellular responses to DNA damage, p53 regulation, and apoptosis mechanisms.

Programmed Cell Death: Mechanisms and Implications

Explores programmed cell death mechanisms, including apoptosis and autophagy, with a focus on their implications in various organisms and regeneration processes.

Evading Growth Suppression: TGFB Signaling

Explores how cells evade growth suppression, focusing on TGFB signaling and the role of tumor suppressors like PTEN and p53.

Altered Pathways in Cancer: Signaling Cascades and Mutations

Explores cancer pathways, major signaling cascades, and mutations in RAS and BRAF genes.

Sustained Proliferation: RTK/PI3K/mTOR Pathway in Cancer

Explores the RTK/PI3K/mTOR pathway in cancer, inhibitors, completed trials, and effects of Akt/PKB on survival and proliferation.

Cell Signalling: Receptors and Pathways

Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, DNA repair, telomeres, viruses, cell cycle, stem cells, metastasis, and genetic instability.

What is cancer? - De Palma

Explores the definition, frequency, classification, and types of cancer, including carcinomas, sarcomas, hematopoietic malignancies, and neuroectodermal tumors.

Altered Metabolism in Cancer: Warburg Effect and MYC Regulation

Explores altered cancer metabolism, MYC regulation, Rb and p53 pathways, AKT re-activation, and protein-protein interactions.

Cellular Senescence and Tumor Progression

Explores cellular senescence, oncogene activation, DNA damage response, and telomere dysfunction in cancer suppression pathways.

Synthetic biology: molecular components and cellular engineering

Delves into synthetic biology, assembling molecular components for biological functions in living cells, including gene expression control and engineered receptor signaling.

Cancer Biology: p53 and DNA Repair

Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.

Tyrosine Kinases & Ras Signaling

Explores tyrosine kinases, Ras activation, lipid signaling, cancer implications, and signal transduction in cells.

Hallmarks of Cancer: Complexity and Capabilities

Explores the complexity and fundamental capabilities of cancer, focusing on hallmarks like sustained proliferative signaling and evading growth suppressors.

Invasion & Metastasis: Mechanisms and Implications

Explores the mechanisms of cancer invasion and metastasis, emphasizing the critical role of cell adhesion, signaling rewiring, and organotropism.

Anti-cancer therapies II: De Palma

Explores breakthroughs in cancer immunotherapy, including immune checkpoint blockade and adoptive T cell therapies.

Melanocytes and Hair Color Regulation

Examines paracrine communication in melanocytes, CAMP influence on hair color, Mc4R mutations, and fur phenotypes.

Active Matter: Cell Dynamics and Modeling

Explores cell dynamics in active matter, focusing on motility, polarity, and signaling pathways in biological systems.

Mutations and Cancer: The Role of P53 and HPV

Covers mutations, the role of P53 in cancer, and HPV's impact on tumorigenesis.

Cell Patterning and Signalling Pathways

Explores cell patterning, signalling pathways, and genetic mutations in biological development.