Lectures related to Pharmacodynamics and Drug Targets

Drug Targets: Receptors, Enzymes, and Therapeutics

Explores drug targets, including receptors, enzymes, and therapeutics, covering pharmacodynamics, case studies on NSAIDs, diabetes, and drug toxicity.

Pharmacological Targets and Interventions

Explores targets for drug action and the design of specific inhibitors.

Renal Pharmacology: Diuretic Drugs and Renin-Angiotensin System

Explores diuretic drugs, renin inhibitors, and ACE inhibitors in renal pharmacology.

Pharmacology: Transporters & Protein Therapeutics

Explores drug targets, protein therapeutics, and anti-TNF agents in pharmacology.

Pharmacodynamics: Acid-sensing ion channels and Drug Targets

Explores acid-sensing ion channels, drug targets, and ligand-receptor binding.

Drug Targets: Receptors, Enzymes, and Transporters

Explores drug targets like receptors, enzymes, and transporters, focusing on top drug indications and receptor-mediated activation of G proteins.

Neurological Disorders: Alzheimer's & Anxiety

Explores Alzheimer's disease, anxiety, pain, and the renin-angiotensin system, including the development of the first renin inhibitor for clinical treatment.

Small Molecule Drugs: Cardiovascular Diseases

Explores the molecular basis and treatment of cardiovascular diseases, focusing on atherosclerosis, hypertension, and drug therapies.

Pharmacology: Drug Targets and Mechanisms

Discusses ligand-receptor binding, drug targets, insulin physiology, NSAIDs, and tyrosine kinase inhibitors.

Activity-based Protein Profiling: Druggable Sites Identification

Explores Activity-based Protein Profiling for druggable site identification and strategies to minimize off-target reactivity of covalent inhibitors.

Micro-ElectroMechanical Systems (MEMS)

Explores Micro-ElectroMechanical Systems (MEMS) development, ion channels, patch clamp technique, drug discovery, and PDMS integration in microfluidic systems.

Renal Pharmacology: Drug Categories and Mechanisms of Action

Explores diuretic drug categories, mechanisms of action, and daily water balance in the kidneys.

Drug Targets: ligand-gated ion channels and kinase-linked receptors

Explores drug targets in ligand-gated ion channels and kinase-linked receptors, focusing on GABAA receptors, benzodiazepines, and insulin therapy.

Chemical Biology meets Drug Discovery

Explores Chemical Biology, Drug Discovery, enzyme kinetics, and inhibition methods, including competitive and non-competitive inhibition.

Interrogating Drugs' Mode of Action

Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.

Pharmacodynamics exercises

Covers the analysis of binding measurements and toxin kinetics in pharmacodynamics.

Inhibitor Design & Analysis

Covers the fundamentals of inhibitor design and analysis, emphasizing the importance of targeting cysteine residues.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.

Enzymes: Catalytic Strategies

Explores enzyme catalytic strategies, including proteases and carbonic anhydrase, inhibition mechanisms, and specificity of serine proteases.

Kinase Inhibitors: Types and Mechanisms Log in to Mediaspace to watch this video

Explores kinase inhibitors, their types, mechanisms, and experimental evaluation, emphasizing the significance of covalent drugs in modern pharmaceutical research.