Lecture

Deep Brain Stimulation: Principles and Programming

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In course

NX-436: Advanced methods for human neuromodulation

Neuromodulation is an expending field especially in human translational neuroscience and neurotechnology. This course will introduce to different approaches / technologies for neuromodulation, their underlying mechanisms of action and application in humans ...

Description

This lecture covers the principles and programming of Deep Brain Stimulation (DBS) for neurological disorders. It discusses the general aspects, computational methods, and closed-loop DBS. The instructor explains the invasive procedures, imaging techniques, and the negative feedback model of the basal ganglia. The lecture also delves into the effects of DBS on Parkinson's disease and dystonia, emphasizing the therapeutic window and pulse width adjustments. Furthermore, it explores the testing of electrodes, monopolar review, and the workflow for programming DBS. The session concludes with insights on altering pulse width to widen the therapeutic window and the challenges in electrode placement.

Instructor

Friedhelm Christoph Hummel

Expertise Stroke recovery Healthy Aging Motor Control Motor Learning Cognitive Control Neuroplasticity Non-invasive Brain Stimulation Structural and functional Neuroimaging Connectivity Postal Address Campus Biotech Defitech Chair of Clinical Neuroengineering Brain Mind Institute, SV Neuro X Institute, Swiss Federal Institute of Technology EPFL Campus Biotech Rm H4.3.132.084, 9, Chemin des Mines 1202 Geneva Teaching & PhD PhD Students Maria Ploumitsakou, Simona Losacco, Fabienne Windel, Andrea Protani, Sta

Official source

Ontological neighbourhood

Health sciences

Neurology: Topics in neurology

Related concepts (30)

Neurological disorder

A neurological disorder is any disorder of the nervous system. Structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. Examples of symptoms include paralysis, muscle weakness, poor coordination, loss of sensation, seizures, confusion, pain and altered levels of consciousness. There are many recognized neurological disorders, some relatively common, but many rare. They may be assessed by neurological examination, and studied and treated within the specialities of neurology and clinical neuropsychology.

Functional neurologic disorder

Functional neurologic disorder or functional neurological disorder (FND) is a condition in which patients experience neurological symptoms such as weakness, movement disorders, sensory symptoms and blackouts. As a functional disorder there is by definition no disease process affecting the structure of the body, yet the person experiences symptoms relating to their body function. Symptoms of functional neurological disorders are clinically recognisable, but are not categorically associated with a definable organic disease.

Deep brain stimulation

Deep brain stimulation (DBS) is a neurosurgical procedure involving the placement of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to specific targets in the brain (the brain nucleus) for the treatment of movement disorders, including Parkinson's disease, essential tremor, dystonia, and other conditions such as obsessive-compulsive disorder (OCD) and epilepsy. While its underlying principles and mechanisms are not fully understood, DBS directly changes brain activity in a controlled manner.

Computational science

Computational science, also known as scientific computing, technical computing or scientific computation (SC), is a division of science that uses advanced computing capabilities to understand and solve complex physical problems. This includes Algorithms (numerical and non-numerical): mathematical models, computational models, and computer simulations developed to solve sciences (e.

Neurological examination

A neurological examination is the assessment of sensory neuron and motor responses, especially reflexes, to determine whether the nervous system is impaired. This typically includes a physical examination and a review of the patient's medical history, but not deeper investigation such as neuroimaging. It can be used both as a screening tool and as an investigative tool, the former of which when examining the patient when there is no expected neurological deficit and the latter of which when examining a patient where you do expect to find abnormalities.

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