Cas9Cas9 (CRISPR associated protein 9, formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein which plays a vital role in the immunological defense of certain bacteria against DNA viruses and plasmids, and is heavily utilized in genetic engineering applications. Its main function is to cut DNA and thereby alter a cell's genome. The CRISPR-Cas9 genome editing technique was a significant contributor to the Nobel Prize in Chemistry in 2020 being awarded to Emmanuelle Charpentier and Jennifer Doudna.
SummationIn mathematics, summation is the addition of a sequence of any kind of numbers, called addends or summands; the result is their sum or total. Beside numbers, other types of values can be summed as well: functions, vectors, matrices, polynomials and, in general, elements of any type of mathematical objects on which an operation denoted "+" is defined. Summations of infinite sequences are called series. They involve the concept of limit, and are not considered in this article.
Tau (particle)The tau (τ), also called the tau lepton, tau particle, tauon or tau electron, is an elementary particle similar to the electron, with negative electric charge and a spin of 1/2. Like the electron, the muon, and the three neutrinos, the tau is a lepton, and like all elementary particles with half-integer spin, the tau has a corresponding antiparticle of opposite charge but equal mass and spin. In the tau's case, this is the "antitau" (also called the positive tau). Tau particles are denoted by the symbol _Tau- and the antitaus by _Tau+.
CRISPRCRISPR (ˈkrɪspər) (an acronym for clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti-phage) defense system of prokaryotes and provide a form of acquired immunity.
Dot productIn mathematics, the dot product or scalar product is an algebraic operation that takes two equal-length sequences of numbers (usually coordinate vectors), and returns a single number. In Euclidean geometry, the dot product of the Cartesian coordinates of two vectors is widely used. It is often called the inner product (or rarely projection product) of Euclidean space, even though it is not the only inner product that can be defined on Euclidean space (see Inner product space for more).
Tau neutrinoThe tau neutrino or tauon neutrino is an elementary particle which has the symbol _Tauon neutrino and zero electric charge. Together with the tau (τ), it forms the third generation of leptons, hence the name tau neutrino. Its existence was immediately implied after the tau particle was detected in a series of experiments between 1974 and 1977 by Martin Lewis Perl with his colleagues at the SLAC–LBL group. The discovery of the tau neutrino was announced in July 2000 by the DONUT collaboration (Direct Observation of the Nu Tau).
Cross productIn mathematics, the cross product or vector product (occasionally directed area product, to emphasize its geometric significance) is a binary operation on two vectors in a three-dimensional oriented Euclidean vector space (named here ), and is denoted by the symbol . Given two linearly independent vectors a and b, the cross product, a × b (read "a cross b"), is a vector that is perpendicular to both a and b, and thus normal to the plane containing them. It has many applications in mathematics, physics, engineering, and computer programming.
SIM cardA SIM card (full form: Subscriber Identity Module or Subscriber Identification Module) is an integrated circuit (IC) intended to store securely the international mobile subscriber identity (IMSI) number and its related key, which are used to identify and authenticate subscribers on mobile telephony devices (such as mobile phones and laptops). Technically the actual physical card is known as a universal integrated circuit card (UICC); this smart card is usually made of PVC with embedded contacts and semiconductors, with the SIM as its primary component.
Video game localizationVideo game localization (American English), or video game localisation (British English; see spelling differences), is the process of preparing a video game for a market outside of where it was originally published. The game's name, art assets, packaging, manuals, and cultural and legal differences are typically altered. Before localization, producers consider economic factors such as potential foreign profit. Most official localizations are done by the game's developers or a third-party translation company.
Internationalization and localizationIn computing, internationalization and localization (American) or internationalisation and localisation (British English), often abbreviated i18n and L10n, are means of adapting computer software to different languages, regional peculiarities and technical requirements of a target locale. Internationalization is the process of designing a software application so that it can be adapted to various languages and regions without engineering changes.
Triple productIn geometry and algebra, the triple product is a product of three 3-dimensional vectors, usually Euclidean vectors. The name "triple product" is used for two different products, the scalar-valued scalar triple product and, less often, the vector-valued vector triple product. The scalar triple product (also called the mixed product, box product, or triple scalar product) is defined as the dot product of one of the vectors with the cross product of the other two.
Sound localizationSound localization is a listener's ability to identify the location or origin of a detected sound in direction and distance. The sound localization mechanisms of the mammalian auditory system have been extensively studied. The auditory system uses several cues for sound source localization, including time difference and level difference (or intensity difference) between the ears, and spectral information.