Course

PHYS-468: Physics of life

Summary

Life has emerged on our planet from physical principles such as molecular self-organization, thermodynamics, stochastics and iterative refinement. This course will introduce the physical methods to study life and will discuss the quantitative and physical concepts that make life possible.

Lectures

Instructor

Henning Paul-Julius Stahlberg

Mission We use high-resolution cryo-electron microscopy to study neurodegeneration and other protein systems. We also develop novel imaging technology in the areas of electron microscopy hardware and applications, sample preparation, data collection schemes, and data analysis software systems. The Stahlberg group is supported by the University of Lausanne, Faculty of Medicine and Biology, and by the EPFL, Faculty of Basic Sciences, Physics Institute. The LBEM is a research laboratory of both UNIL and EPFL.

Official source

https://edu.epfl.ch/coursebook/en/physics-of-life-PHYS-468

Moodle Page

http://go.epfl.ch/PHYS-468

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Summary

Lectures

Instructor

Henning Paul-Julius Stahlberg

Official source

https://edu.epfl.ch/coursebook/en/physics-of-life-PHYS-468

Moodle Page

http://go.epfl.ch/PHYS-468

About this result

Lectures in this course (21)

Fourier Transform Applications: Image Processing Basics

Covers image processing basics, Fourier transformation, convolution, cross-correlation, and 3D reconstruction using the Radon projection theorem.

ATP Synthase: Molecular Machine and Energy Production

Explores the F-type ATP Synthase, a molecular machine crucial for energy production in cells, covering its structure, function, and energy production mechanisms.

Protein Folding: Forces and Mechanisms

Explores protein folding forces, including van der Waals interactions, hydrogen bonds, and salt bridges, and their impact on stability.

ATP Synthase: Efficiency and Mechanisms

Delves into the efficiency and mechanisms of ATP Synthase, covering its model, engine efficiency, energy production, and structural insights.

Characterization of Proteins by Electrophoresis

Explores the physics of electrophoresis for protein characterization, covering Native Gel, SDS-PAGE, and 2D Gel.

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