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ME-482: Biomechanics of the musculoskeletal system

Summary

The basis for a mechanical description of the musculoskeletal system are presented. This description is based on the concepts of solid mechanics, physiology and anatomy of the musculoskeletal system. Concrete examples of the development of implants are also covered.

Lectures

Instructor

Dominique Pioletti

Dominique Pioletti received his Master in Physics from the Swiss Federal Institute of Technology Lausanne (EPFL) in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws taking into account viscoelasticity in large deformations. Then he spent two years at UCSD as post-doc fellow acquiring know-how in cell and molecular biology. He was interested in particular to gene expression of bone cells in contact to orthopedic implant. In April 2006, Dominique Pioletti was appointed Assistant Professor tenure-track at the EPFL and is director of the Laboratory of Biomechanical Orthopedics. His research topics include biomechanics and tissue engineering of musculo-skeletal tissues; mechano-transduction in bone; development of orthopedic implant as drug delivery system. Since 2013, he has been promoted to the rank of Associate Professor.

Official source

https://edu.epfl.ch/coursebook/en/biomechanics-of-the-musculoskeletal-system-ME-482

Moodle Page

http://go.epfl.ch/ME-482

Summary

Lectures

Instructor

Dominique Pioletti

Official source

https://edu.epfl.ch/coursebook/en/biomechanics-of-the-musculoskeletal-system-ME-482

Moodle Page

http://go.epfl.ch/ME-482

Ontological neighbourhood

Health sciences

Surgery: Orthopedics

Chemical engineering

Materials science: Deformation of materials

Lectures in this course (20)

Neuromuscular Junction Log in to Mediaspace to watch this video

Covers the nervous system's control of muscle contraction through motor units at the neuromuscular junction.

Functional Anatomy: Bone Structure and Mechanical Properties

Explores bone functional anatomy, including structure, support, and protection, as well as cartilage and ligament biomechanics.

Biomechanical Tissues: Non-linear Constitutive Laws Log in to Mediaspace to watch this video

Explores biomechanics at the tissue level, focusing on constitutive laws, stress-strain curves, and treatment options for ACL rupture.

Tissue Mechanical Remodeling Log in to Mediaspace to watch this video

Covers mechanical stimulus in tissue remodeling, bone density, hip implant modeling, and finite element analysis.

Tissue Mechanical Remodeling Log in to Mediaspace to watch this video

Delves into bone biomechanics, adaptation at different time scales, and the influence of mechanical stimulus on bone density evolution.

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