Course

CH-335: Asymmetric synthesis and retrosynthesis

Summary

The first part of the course presents the classical methods of asymmetric synthesis. The second part of the course introduces retrosynthesis strategies based on the disconnection approach.

Lectures

Instructors (2)

Sandrine Gerber

Sandrine Gerber studied chemistry at the "Ecole Nationale Supérieure de Chimie de Paris" in France, where she obtained a diploma of chemical engineer in 1993. The same year she obtained a DEA (Master degree) of organic chemistry at the University Pierre et Marie Curie (Paris VI, France). From 1993 to 1996 she did a PhD in organic chemistry under the supervision of Prof. Jean-Pierre Genêt at the Ecole Nationale Supérieure de Chimie de Paris. In 1996, she moved to University of Lausanne for a post-doctoral stay under the supervision of Prof. Pierre Vogel. In 1998, she was appointed Maître-Assistante at the Institute of Organic Chemistry in the University of Lausanne. In 2003, she obtained the habilitation to direct research from the University Pierre et Marie Curie (Paris VI, France). The same year, she was appointed scientific adjunct at the EPFL and senior scientist (Maître d'Enseignement et de Recherche) in 2006. In December 2014, she was promoted to titular professor. Since September 2007, Sandrine Gerber is deputy to the director of the Institute of Chemical Sciences and Engineering (ISIC). She is also member of the Board of Directors of the Swiss Chemical Society. Since 2007, Sandrine Gerber is part-time lecturer at the university of Fribourg. She was awarded the Prize Eugene Schueller in 1997, the Prize Dufour for prospective organic chemistry in 2005 and the Werner Prize 2010. She also received a special mention in recognition of exceptional quality of pedagogic competencies in the teaching of basic sciences, given by the Direction of the School of Biology and Medicine from the University of Lausanne, in 2013. In October 2018, she will receive the Prize for Excellence in Teaching from the section of Chemistry and Chemical Engineering.

Stefano Nicolai

Teaching & PhD Courses Asymmetric synthesis and retrosynthesis CH-335 The first part of the course presents the classical methods of asymmetric synthesis. The second part of the course introduces retrosynthesis strategies based on the disconnection approach.

Official source

Moodle Page

http://go.epfl.ch/CH-335

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Summary

The first part of the course presents the classical methods of asymmetric synthesis. The second part of the course introduces retrosynthesis strategies based on the disconnection approach.

Lectures

Instructors (2)

Sandrine Gerber

Stefano Nicolai

Official source

Moodle Page

http://go.epfl.ch/CH-335

Lectures in this course (39)

Protecting Groups in Organic Synthesis

Explores the use of protecting groups in organic synthesis, emphasizing stability and selectivity.

Aromatic Compounds: Retrosynthesis Principles

Covers the retrosynthesis of aromatic compounds, focusing on basic principles and the synthesis route.

Retrosynthesis: Basic Principles

Covers the basic principles of retrosynthesis, focusing on disconnections C-X and C-C.

Retrosynthesis: Basic Principles and Aromatic Compounds

Covers the basic principles of retrosynthesis and aromatic compounds in organic synthesis.

Retrosynthesis: Disconnections C-C

Covers the principles of retrosynthesis, focusing on disconnections C-C and functional group disconnections.

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