Course

BIO-478: Pharmacology and pharmacokinetics

Summary

This course introduces the student to the fudamentals of pharmacology, pharmacokinetics and drug-receptor interactions. It discusses also pharmacogenetics and chronopharmacology, to exemplify the challenges of personalized medicine.

Lectures

Instructors (2)

Dmitri Firsov

Teaching & PhD Courses Pharmacology and pharmacokinetics BIO-478 This course introduces the student to the fudamentals of pharmacology, pharmacokinetics and drug-receptor interactions. It discusses also pharmacogenetics and chronopharmacology, to exemplify the challenges of personalized medicine.

Stephan Beat Kellenberger

Teaching & PhD Courses Basic principles of drug action at the cardiovascular system CH-602 The aim of this course is two-fold:- to describe the molecular properties of some important drug targets- to illustrate some applications of drugs active at the nervous and cardiovascular systems. Basic principles of drug action at the nervous system CH-603 The aim of this course is two-fold:i) to describe the molecular properties of some important drug targetsii) to illustrate some app

Official source

https://edu.epfl.ch/coursebook/en/pharmacology-and-pharmacokinetics-BIO-478

Moodle Page

http://go.epfl.ch/BIO-478

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Summary

Lectures

Instructors (2)

Dmitri Firsov

Stephan Beat Kellenberger

Official source

https://edu.epfl.ch/coursebook/en/pharmacology-and-pharmacokinetics-BIO-478

Moodle Page

http://go.epfl.ch/BIO-478

Lectures in this course (11)

Drug Targets: Nuclear Receptors

Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.

Pharmacodynamics: Ligand Concentration, Binding, and Effect

Explores the relationship between ligand concentration, binding, and effect, focusing on allosteric modulators and types of pharmacological antagonists.

Drug Targets: Ligand-Gated Ion Channels and Kinase-Linked Receptors

Explores drug targets like ligand-gated ion channels and kinase-linked receptors, discussing mechanisms of action, clinical uses, and insulin's physiological context.

Neurotransmitter Glutamate: Receptor Dynamics and Pharmacodynamics

Explores neurotransmitter dynamics, receptor interactions, and pharmacological concepts in CNS synapses.

Pharmacology of Pain: Mechanisms and Drug Targets

Explores the pharmacology of pain, including nociceptive pain, sensitizing agents, opioid receptor agonists, NSAIDs, and drug mechanisms.