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Course

BIO-212: Biological chemistry I

Lectures in this course (76)

Electron Transport Chain: Mitochondrial Respiration

Explores the electron transport chain and oxidative phosphorylation in mitochondria, focusing on ATP production and reactive oxygen species.

ATP Synthase: Structure and Mechanism

Explores the structure and mechanism of ATP synthase, focusing on how it generates ATP molecules using a proton gradient and the interconversion of beta subunit states.

Lipids: Structure, Function, and Synthesis

Explores the structure, function, and synthesis of lipids, including fatty acid composition and enzymatic processes.

Glycerophospholipid Synthesis

Covers the synthesis of glycerophospholipids, triglycerides, phospholipids, and cholesterol from basic precursors.

Gluconeogenesis: Biosynthesis of Carbohydrates

Explores gluconeogenesis, the production of glucose from non-sugar precursors, and its importance for energy production in the body.

Glycolysis and Gluconeogenesis

Explores the regulation of glucose metabolism, focusing on glycolysis, gluconeogenesis, and glycogen metabolism.

Immunoengineering: Antibody Responses

Explores immunoengineering strategies to modulate antibody responses and immunodominance in vaccine development.

Intermolecular Interactions: Energy Functions & Protein Structure

Explores empirical energy functions, bond potentials, van der Waals interactions, and Coulomb's law in molecular interactions.

Protein Phosphorylation: Mechanisms & Regulation

Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.

Proteomics: Post-Translational Modifications and Interactions

Explores proteomics for post-translational modifications and protein interactions.

Molecular Glues: New Drug Modalities

Explores molecular glues as new drug modalities, focusing on binding forces, energetics, biomolecular interactions, quantification, drug development, and structural characterization.

Metabolism and Hormones

Explores metabolic processes in different tissues and the role of hormones.

Metabolic Hormones: Insulin and Glucagon

Explores how insulin and glucagon regulate blood glucose levels through intricate mechanisms involving various organs and signaling pathways.

Protein Structure and Analysis

Covers protein structure, post-translational modifications, and analysis techniques.

Protein Folding: Principles and Thermodynamics

Explores protein folding principles, thermodynamics, Boltzmann distribution, and NMR structures in biomolecules.

Protein Structure Analysis

Covers the analysis of protein structures using PyMOL software and the visualization of amino acid sequences and residues.