Explores membrane protein quality control mechanisms at the ER, focusing on ERAD recognition, retrotranslocation, ubiquitination, and degradation of misfolded proteins.
Covers the mechanisms of protein localization in cells, focusing on synthesis, sorting, and transport pathways involving the endoplasmic reticulum and Golgi apparatus.
Explores the synthesis of sphingolipids, focusing on ceramide formation, glycosylation, and sphingomyelin conversion, as well as the biosynthesis of complex glycosphingolipids.
Explores proximity-specific ribosome profiling and translational dynamics with high resolution, covering translation in different cells and the ER's role in protein synthesis.
Explores the regulation of motor activity in kinesins, dynein structure, organelle movement, cilia assembly, and biological implications of microtubule defects.