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Concept

Spasticity

Related publications (12)

System for control of spasticity

Grégoire Courtine, Jocelyne Bloch, Fabien Bertrand Paul Wagner, Robin Jonathan Demesmaeker, Salif Axel Komi, Karen Minassian

The present invention relates to a neuromodulation/neurostimulation system (10) for the treatment of spasticity in a mammal, said system (10) comprising: - at least one control unit (12) configured and arranged to provide stimulation data, and - at least o ...

2024

Filiform Variable Stiffness Technologies for Medical Robotics

Yegor Piskarev

In recent years, soft robotics has surged in applications like wearables, drones, smart fabrics, and medical instruments. Due to their compliance, these devices excel in tasks demanding dexterity and adaptability, such as manipulation, locomotion, crash re ...

EPFL2024

Sensory modulation of gait characteristics in human locomotion: A neuromusculoskeletal modeling study

Auke Ijspeert, Andrea Di Russo, Dimitar Yuriev Stanev

The central nervous system of humans and other animals modulates spinal cord activity to achieve several locomotion behaviors. Previous neuromechanical models investigated the modulation of human gait changing selected parameters belonging to CPGs (Central ...

2021

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)

Friedhelm Christoph Hummel, Simone Rossi

A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations t ...

ELSEVIER IRELAND LTD2020

The effects of dual tasks on gait in children with cerebral palsy

Kamiar Aminian, Lena Carcreff

Aim: To assess the gait and cognitive performances of children with cerebral palsy (CP) during dual tasks (DT) in comparison to typically developing (TD) children. Method: This prospective, observational, case-control study included 18 children with CP (7 ...

2019

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

Mohamed Bouri, Solaiman Shokur, Miguel Nicolelis

Spinal cord injury (SCI) impairs the flow of sensory and motor signals between the brain and the areas of the body located below the lesion level. Here, we describe a neurorehabilitation setup combining several approaches that were shown to have a positive ...

Nature Research2019

Muscle activities in similar arms performing identical tasks reveal the neural basis of muscle synergies

Martina Coscia

Are the muscle synergies extracted from multiple electromyographic signals an expression of neural information processing, or rather a by-product of mechanical and task constraints? To address this question, we asked 41 right-handed adults to perform a var ...

SPRINGER2020

From bio-inspired locomotion models To controllers for lower-limb exoskeletons

Florin Dzeladini

Human locomotion shows fascinating abilities which are the results of the interplay between the environment, the biomechanics, the spinal cord, and modulation from higher control centers. How the different structures interact to generate meaningful behavio ...

EPFL2019

Hand perceptions induced by single pulse transcranial magnetic stimulation over the primary motor cortex

Olaf Blanke, Andrea Serino, Michela Bassolino, Matteo Franza

Background When single pulse transcranial magnetic stimulation (TMS) is applied over the primary motor cortex (M1) with sufficient intensity, it evokes muscular contractions (motor-evoked potentials, MEPs) and muscle twitches (TMS-evoked movements). Partic ...

2019

Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease

Johan Auwerx, Laia Morato Fornaguera

Pelizaeus-Merzbacher disease (PMD) is a fatal hypomyelinating disorder characterized by early impairment of motor development, nystagmus, choreoathetotic movements, ataxia and progressive spasticity. PMD is caused by variations in the proteolipid protein g ...

2018

Model-based variables for the kinematic assessment of upper-extremity impairments in post-stroke patients

Silvestro Micera, Elvira Pirondini

Background: Common scales for clinical evaluation of post-stroke upper-limb motor recovery are often complemented with kinematic parameters extracted from movement trajectories. However, there is no a general consensus on which parameters to use. Moreover, ...

BioMed Central2016

Deficient mental own-body imagery in a neurological patient with out-of-body experiences due to cannabis use

Olaf Blanke

In the present work, we report repeated out-of-body experiences (OBEs) in a patient with tetraplegia and severe somatosensory loss due to multiple sclerosis and predominant involvement of the cervical spinal cord. OBEs were experienced on a daily basis and ...

Elsevier Masson2009