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Related publications (29)

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Excitatory/inhibitory neuronal metabolic balance in mouse hippocampus upon infusion of [U-C-13(6)]glucose

Rolf Gruetter, Hongxia Lei, Bernard Lanz, Carole Poitry-Yamate, Antoine Timothée Cherix, Guillaume Donati, Blanca Lizarbe Serra

Hippocampus plays a critical role in linking brain energetics and behavior typically associated to stress exposure. In this study, we aimed to simultaneously assess excitatory and inhibitory neuronal metabolism in mouse hippocampus in vivo by applying (18) ...

2021

Projection-specific Activity of Layer 2/3 Neurons Imaged in Mouse Primary Somatosensory Barrel Cortex During a Whisker Detection Task

Sylvain Crochet

The brain processes sensory information in a context- and learning-dependent manner for adaptive behavior. Through reward-based learning, relevant sensory stimuli can become linked to execution of specific actions associated with positive outcomes. The neu ...

2020

Spatiotemporal Maps of Proprioceptive Inputs to the Cervical Spinal Cord During Three-Dimensional Reaching and Grasping

Auke Ijspeert, Marco Capogrosso, Nathan Antoine Greiner, Shravan Tata Ramalingasetty, Pierre Charles Marie Kibleur

Proprioceptive feedback is a critical component of voluntary movement planning and execution. Neuroprosthetic technologies aiming at restoring movement must interact with it to restore accurate motor control. Optimization and design of such technologies de ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

The Cortical States of Wakefulness

Sylvain Crochet

Cortical neurons process information on a background of spontaneous, ongoing activity with distinct spatiotemporal profiles defining different cortical states. During wakefulness, cortical states alter constantly in relation to behavioral context, attentio ...

2019

Neural Circuits for Goal-Directed Sensorimotor Transformations

Carl Petersen, Sylvain Crochet

Precisely wired neuronal circuits process sensory information in a learning- and context-dependent manner in order to govern behavior. Simple sensory decision-making tasks in rodents are now beginning to reveal the contributions of distinct cell types and ...

ELSEVIER SCIENCE LONDON2019

N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study

Rolf Gruetter, Patric Hagmann, Lijing Xin, Alessandra Griffa

Background: There is increasing evidence that redox dysregulation, which can lead to oxidative stress and eventually to impairment of oligodendrocytes and parvalbumin interneurons, may underlie brain connectivity alterations in schizophrenia. Accordingly, ...

Oxford University Press (OUP)2019

Cellular, Synaptic and Network Effects of Acetylcholine in the Neocortex

Henry Markram, Daniel Keller, Srikanth Ramaswamy, Cristina Colangelo, Polina Shichkova

The neocortex is densely innervated by basal forebrain (BF) cholinergic neurons. Long-range axons of cholinergic neurons regulate higher-order cognitive function and dysfunction in the neocortex by releasing acetylcholine (ACh). ACh release dynamically rec ...

2019

Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex

Carl Petersen, Berat Semihcan Sermet, Johannes Maria Mayrhofer

Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information, receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial (VPM) somatosensory thalamic nucleus most densely innervates layer 4 (L4) bar ...

2019

Untangling emergent cortical dynamics: neurons from networks, noise from chaos

Max Christian Nolte

The way in which cortical microcircuit components -- most importantly neurons -- and their connectivity -- the network -- shape and constrain emergent dynamics is a long-standing question in neuroscience. Experimentally observed dynamical properties can of ...

EPFL2019