Concept

Multiple comparisons problem

Related publications (30)

Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link

Jacques Fellay, Christian Axel Wandall Thorball

Background: Considering the remaining threat of drug-resistantmutations (DRMs) to antiretroviral treatment (ART) efficacy, we investigated how the selective pressure of human leukocyte antigen (HLA)-restricted cytotoxic T lymphocytes drives certain DRMs' e ...

2021

Discrete-Choice Mining of Social Processes

Victor Kristof

Poor decisions and selfish behaviors give rise to seemingly intractable global problems, such as the lack of transparency in democratic processes, the spread of conspiracy theories, and the rise in greenhouse gas emissions. However, people are more predict ...

EPFL2021

Trends in the Extremes of Environments Associated with Severe US Thunderstorms

Anthony Christopher Davison, Erwan Fabrice Koch, Jonathan Koh Boon Han

Severe thunderstorms can have devastating impacts. Concurrently high values of convective available potential energy (CAPE) and storm relative helicity (SRH) are known to be conducive to severe weather, so high values of PROD - (CAPE)(1/2) x SRH have been ...

AMER METEOROLOGICAL SOC2021

A comprehensive error rate for multiple testing

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Stephan Morgenthaler, Djalel Eddine Meskaldji

Over the last two decades, a large variety of type I error rates and control procedures have been proposed in the field of multiple hypotheses testing. This paper proposes a framework that includes many existing proposals by investigating procedures in whi ...

SPRINGER2020

The diagnostic potential of multimodal neuroimaging measures in Parkinson's disease and atypical parkinsonism

Chang-Hyun Park

Introduction For the diagnosis of Parkinson's disease (PD) and atypical parkinsonism (AP) using neuroimaging, structural measures have been largely employed since structural abnormalities are most noticeable in the diseases. Functional abnormalities have b ...

2020

Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation

Tobias Kober, Tom Hilbert

Objectives This study evaluates GRAPPATINI, an accelerated T-2 mapping sequence combining undersampling and model-based reconstruction to facilitate the clinical implementation of T-2 mapping of the lumbar intervertebral disc. Methods Fifty-eight individua ...

SPRINGER2021

Max-infinitely divisible models and inference for spatial extremes

Raphaël Huser, Emeric Rolland Georges Thibaud

For many environmental processes, recent studies have shown that the dependence strength is decreasing when quantile levels increase. This implies that the popular max-stable models are inadequate to capture the rate of joint tail decay, and to estimate jo ...

WILEY2021

Sublinear Bounds on the Distinguishing Advantage for Multiple Samples

Serge Vaudenay

The maximal achievable advantage of a (computationally unbounded) distinguisher to determine whether a source

Z

is distributed according to distribution

P_0

P_1

, when given access to one sample of

Z

, is characterized by the statistical distance ...

Springer, Cham2020

Exploring the interactions between the human and viral genomes

Jacques Fellay

Over the last decade, genome-wide association studies led to major advances in identifying human genetic variants associated with infectious disease susceptibility. On the pathogen side, comparable methods are now applied to identify disease-modulating pat ...

SPRINGER2020

Multiscale simulation of erosive wear in a prototype-scale Pelton runner

François Avellan, Ebrahim Jahanbakhsh, Sebastián Camilo Leguizamón Sarmiento, Siamak Alimirzazadeh

The technical capacity to predict the erosion process is instrumental for the optimization of the runner designs and operation strategies of hydroelectric plants. A multiscale model of erosion recently formulated by the authors and validated on a laborator ...

Pergamon-Elsevier Science Ltd2020