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Concept

Radiocontrast agent

Related publications (29)

Superparamagnetic nanohybrids with cross-linked polymers providing higher in vitro stability

Heinrich Hofmann, Lionel André Maurizi

A simple, rapid, reproducible, and scalable method for generating highly stable cross-linked superparamagnetic nanohybrids was developed. Pre-coating of superparamagnetic iron oxide nanoparticle surfaces with a biocompatible polymer, hydroxy polyvinyl alco ...

Springer Verlag2017

From closed testaments to books: Virtual X-ray Reading as an alternate digitization technology for fragile documents

Giorgio Margaritondo, Demetri Psaltis, Fauzia Albertin

In recent years, research and technology made considerable progress in increasing the speed and the safety of the entire digitization process of ancient collections. Despite this, imaging ancient, fragile or un-opened documents remains a formidable challen ...

Soc Imaging Science & Technology2017

Superparamagnetic Nanoparticles as High Efficiency Magnetic Resonance Imaging T-2 Contrast Agent

Francesco Stellacci, Henrik Moodysson Rønnow, Kurt Schenk, Paulo Henrique Jacob Silva, Randy Patrick Carney, Lin Yang, Ping Huang, Arash Alahgholipour Omrani

Nanoparticle-based magnetic resonance imaging T-2 negative agents are of great interest, and much effort is devoted to increasing cell loading capability while maintaining low cytotoxicity. Herein, two classes of mixed-ligand protected magnetic-responsive, ...

American Chemical Society2017

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Francesco Stellacci, Li Tang, Ahmet Bekdemir

Inorganic nanoparticles (NPs) are studied as drug carriers, radiosensitizers and imaging agents, and characterizing nanoparticle biodistribution is essential for evaluating their efficacy and safety. Tracking NPs at the single-cell level with current techn ...

Nature Publishing Group2017

Chelating agents as coating molecules for iron oxide nanoparticles

Heinrich Hofmann, Josefina Adriana Maria Bastiaansen, Marijana Mionic Ebersold, Débora Bonvin

Due to their high chemical affinity towards metal ions, chelating agents (CAs) have been used for decades for water purification, but also for protection against metal intoxication and in nanomedicine as linking molecules at the surface of nanoparticles. H ...

RSC Publishing2017

Evaluation of Water Exchange Kinetics on [Ln(AAZTAPh–NO2)(H2O)q]x Complexes Using Proton Nuclear Magnetic Resonance

Lothar Helm, Shima Karimi

Water exchange kinetics on [Ln(AAZTAPh–NO2)(H2O)q]− (Ln = Gd3+, Dy3+, or Tm3+) were determined by 1H nuclear magnetic resonance (NMR) measurements. The number of inner-sphere water molecules was found to change from two to one when going from Dy3+ to Tm3+. ...

American Chemical Society2016

The Necrosis-Avid Small Molecule HQ4-DTPA as a Multimodal Imaging Agent for Monitoring Radiation Therapy-Induced Tumor Cell Death

Riccardo Sinisi

Purpose: Most effective antitumor therapies induce tumor cell death. Non-invasive, rapid and accurate quantitative imaging of cell death is essential for monitoring early response to antitumor therapies. To facilitate this, we previously developed a biocom ...

Frontiers Media Sa2016

Transient versus Static Electron Spin Relaxation in Mn2+ Complexes Relevant as MRI Contrast Agents

Lothar Helm

The zero,-field splitting (ZFS) parameters of the Mn(EDTA)(H2O).2H(2)O. and [Mn(MeNO(2)A)(H2O)].2H(2)O systems were estimated by using DFT and ab initio CASSCF/NEVPT2 calculations (EDTA = (ethane-1,2-41bis(azanetriy1))tetraatetate; MeNO2A = 2,2'-(7-m ...

American Chemical Society2016

Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord

Peter Modregger

Faults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal system represents a c ...

Nature Publishing Group2015