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Concept

Depression (mood)

Related publications (30)

Electrophysiological correlates of visual backward masking in patients with major depressive disorder

Michael Herzog, Maya Roinishvili, Patricia Figueiredo, Ophélie Gladys Favrod, Janir Nuno Ramos Antunes Da Cruz

Depression and schizophrenia are two psychiatric diseases with high co-morbidity. For this reason, it is important to find sensitive endophenotypes, which may disentangle the two disorders. The Shine-Through paradigm, a visual backward masking task, is a p ...

2019

Depersonalization- and derealization-like phenomena of epileptic origin

Olaf Blanke, Lukas Heydrich, Nathaniel Evans

Objective Depersonalization refers to the sensation of being detached from one's body, often associated with feelings of loss of control over one's own body, actions, or thoughts. Derealization refers to the altered perception of one's surroundings that is ...

2019

Nucleus accumbens neurochemistry in human anxiety: A 7 T 1H-MRS study

Rolf Gruetter, Maria del Carmen Sandi Perez, Lijing Xin, Alina Veronika Irene Strasser

Individual differences in anxiety provide a differential predisposition to develop neuropsychiatric disorders. The neurochemical underpinnings of anxiety remain elusive, particularly in deep structures, such as the nucleus accumbens (NAc) whose involvement ...

2019

Stress-Induced Depression: Is Social Rank a Predictive Risk Factor?

Maria del Carmen Sandi Perez, Thomas Didier Larrieu

An intriguing question in the field of stress is what makes an individual more likely to be susceptible or resilient to stress‐induced depression. Predisposition to stress susceptibility is believed to be influenced by genetic factors and early adversity. ...

2018

Quantification Of Resting-State Fmri Networks Driven By Hemodynamically Informed Spatiotemporal Regularization

Dimitri Nestor Alice Van De Ville, Fikret Isik Karahanoglu, Younes Farouj

The brain's spontaneous fluctuations measured by functional magnetic resonance imaging during rest cluster into recurrent activity patterns known as resting-state networks (RSNs). The spatial organization of RSNs in health and disease has been immensely in ...

IEEE2018

A novel electrochemical sensor for non-invasive monitoring of lithium levels in mood disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main drug for the treatment of mood disorders. Due to its narrow therapeutic window, Therapeutic Drug Monitoring (TDM) is a norm during therapy in order to avoid adverse effects. Consequently, patients are obliged to frequent check-ups in ho ...

2018

High anxiety trait: A vulnerable phenotype for stress-induced depression

Maria del Carmen Sandi Perez, Meltem Weger

A great deal of research aims to identify risk factors related to individual vulnerability to develop stress-induced psychopathologies. Here, we summarize evidence that point at anxiety trait as a significant contributor to inter-individual differences in ...

2018

Long term programming of psychopathology-like behaviors in male rats by peripubertal stress depends on individual’s glucocorticoid responsiveness to stress

Maria del Carmen Sandi Perez, Sophie Elizabeth Walker

Experience of adversity early in life and dysregulation of hypothalamus–pituitary–adrenocortical (HPA) axis activity are risk factors often independently associated with the development of psychopathological disorders, including depression, PTSD and pathol ...

2018

Hierarchical status predicts behavioral vulnerability and nucleus accumbens metabolic profile following chronic social defeat stress

Rolf Gruetter, Maria del Carmen Sandi Perez, Hongxia Lei, João Pedro de Matos Rodrigues, Antoine Timothée Cherix, Thomas Didier Larrieu

Extensive data highlight the existence of major differences in individuals’ susceptibility to stress [1; 2; 3 ; 4]. While genetic factors [5 ; 6] and exposure to early life stress [7 ; 8] are key components for such neurobehavioral diversity, intriguing ob ...

2017

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression

Pierre Magistretti

Recent studies implicate the arginine-decarboxylation product agmatine in mood regulation. Agmatine has antidepressant properties in rodent models of depression, and agmatinase (Agmat), the agmatine-degrading enzyme, is upregulated in the brains of mood di ...

Nature Publishing Group2016