Pierre-Emmanuel DessemontetExpertise
- Urban and suburban economic geography and spatial economy- Spatial statistical methods as applied in human geography, including new research paths such as spatial autocorrelation effect mitigation, distance matrices- Encyclopedic knowledge of census records and techniques, in Switzerland and Europe
Expertise
- Urban and suburban economic geography and spatial economy- Spatial statistical methods as applied in human geography, including new research paths such as spatial autocorrelation effect mi
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Jan SkaloudExpertise
Satellite positioning, inertial and integrated navigation Sensor orientation and calibration, attitude determination Mobile mapping, airborne laser scanning Adjustment methods, Kalman Filtering
Mission
Teaching in 3 EPFL sections and 2 faculties, director of ESO lab.
Books / Monographs J. Skaloud and M. Cramer, «Data Capture,» in GIS Handbook, W. Kresse and D. Danko, Eds. Springer, 2011. D. Lichti and J. Skaloud, «Registration and Calibration,» in Airborne and terrestrial laser scanning, H.-G. Ma
Patrick ThiranPatrick Thiran is a full professor in network and systems theory at the School of Computer and Communication Sciences at EPFL. He holds an electrical engineering degree from the Université Catholique de Louvain, Louvain-la-Neuve, Belgium, an M.Sc. degree in electrical engineering from the University of California at Berkeley, USA, and he received the PhD degree from EPFL, in 1996. He became an adjunct professor in 1998, an assistant professor in 2002, an associate professor in 2006 and a full professor in 2011. He was with Sprint Advanced Technology Labs in Burlingame, California, in 2000-01.
His research interests are in communication and social networks, performance analysis and stochastic models. He is currently active in the analysis and design of wireless and PLC networks (scaling laws, medium access control), in network monitoring (network tomography, multi-layer networks), and data-driven network science. He also contributed to network calculus and to the theory of locally coupled neural networks and self-organizing maps.
He served as an associate editor for the IEEE Transactions on Circuits and Systems in 1997-99 and for the IEEE/ACM Transactions on Networking in 2006-10. He is currently on the editorial board of the IEEE Journal on Selected Areas in Communication. He is/was on the program committee of different conferences in networking, including ACM Sigcomm, Sigmetrics, IMC, CoNext and IEEE Infocom. He was TPC chair of AMC IMC 2011 and CoNext 2012. He is a Fellow of the Belgian American Educational Foundation and of the IEEE. He received the 1996 EPFL Doctoral Prize and the 2008 Crédit Suisse Teaching Award.
Antoine BosselutAntoine Bosselut is an assistant professor at EPFL. He leads the EPFL NLP group, which conducts research on natural language processing (NLP) systems that can model, represent, and reason about human and world knowledge.
Prior to joining EPFL, he was a postdoctoral researcher at Stanford University working in the
SNAP
and
NLP
groups and a young investigator on the
Mosaic
project at the
Allen Institute for AI
. He completed his PhD at the University of Washington.
Pierre-Yves GilliéronHe graduated in Surveying Engineering at the Swiss Federal Institute of Technology Lausanne in 1988. He started his professional career in photogrammetry and digital mapping. He joined the Geodetic Eng. Laboratory in 1997 where he worked as research scientist on various navigation and satellite positioning projects.
Since 2018 he is deputy head of the section in environmental sciences and engineering at EPFL.
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He was member of the board of the swiss institute of navigation (ION-CH), member of the swiss geodetic committee (SGK) and expert in different committees of the swiss road association (VSS).
Isabella Di LenardoPh.D. in Theories and Art History. Isabella di Lenardo is senior scientist in Digital Humanities and Urban History. Her research activity is focused on digital tools and methods applied to Urban History. She is an expert in ancient cartography, city representations, cadastral sources interpreted through digital modeling, extraction and analysis systems.She's also interested in network analysis questioning the production and circulation of artistic and architectural knowledge in Europe XVIth – XVIIIth centuries in particular on North-South relationships and influences. The development of collaboration projects with European institutions and the activity carried out on various initiatives supported by the European Commission have allowed her to acquire specialism in the field of science applied to heritage, developing in particular specific skills for the enhancement of Cultural Heritage through digital tools. She leads projects in collaboration with Bibliothèque national de France (Paris), Institut National d’Histoire de l’Art (Paris), Ecole nationale des chartes (Paris), Université Paris I Panthéon-Sorbonne, Centre Allemand d’Histoire de l’Art (Paris), Musée du Louvre, Archives Nationales de Paris, Bibliothèque Historique de la Ville de Paris, Réunion des Musées Nationaux. She supervised all the urban modeling simulations for the Venice Time Machine project and acted as content curator for all the exhibitions (Venice Biennale, Grand Palais-Paris, Datasquare - ArtLab-Lausanne, Museo Correr-Venice). She was Head of “Replica” project : digitizing 1 million photos of artworks in the Fondazione Giorgio Cini (Venice) and visual patterns extraction through a search engine for visual similarities. She has a Ph.D in Art History and also studied Archaeology and Urban Studies. She has published essays and articles about Venetian Art and Urban History and participated in many Art exhibitions in European museums. She coordinated summer schools and workshops about Digital Tools for Art History and Urban History. She attended conferences on digital methods for History in universities and patrimonial institutions.
Rémi Guillaume PetitpierreTeaching & PhDDigital urban history: Lausanne Time Machine HUM-450, HUM-454 - Teaching assistant. Website
Michaël UnserExpertise
Image Processing, Medical Imaging, Biological Imaging, Wavelets, Splines, Multiresolution
Michael Unser is Full Professor with EPFL’s school of Engineering and the academic director of EPFL's Center for Imaging, Lausanne, Switzerland. His primary areas of investigation are signal processing, biomedical imaging and applied functional analysis. He is internationally recognized for his research contributions to sampling theory, wavelets, the use of splines for image processing, stochastic processes,
Devis TuiaI come from Ticino and studied in Lausanne, between UNIL and EPFL. After my PhD at UNIL in remote sensing, I was postdoc in Valencia (Spain), Boulder (CO) and EPFL, working on model adaptation and prior knowledge integration in machine learning. In 2014 I became Research Assistant Professor at University of Zurich, where I started the 'multimodal remote sensing' group. In 2017, I joined Wageningen University (NL), where I was professor of the GeoInformation Science and Remote Sensing Laboratory. Since 2020, I joined EPFL Valais, to start the ECEO lab, working at the interface between Earth observation, machine learning and environmental sciences.
Ronan BoulicI come from Brittany, France, where I have completed my PhD degree in Computer Science in 1986 from the University of Rennes, France, at the INRIA-IRISA research institute. I also received the Habilitation degree from the University of Grenoble, France, in march 1995. I was hired in 1989 as First Assistant in the VRLAB, I became scientific collaborator, and senior researcher. I'm presently Senior Scientist (MER) and leader of the Immersive Interaction research Group (IIG). I'm co-author of around 150 research papers among which 43 appeared in international peer-reviewed journals. I have contributed to multiple SNF projects and EU projects. Please check iig.epfl.ch for more details.
Armel Firmin Kemajou MbiandaTravail en cours
La construction des périphéries urbaines en Afrique subsaharienneSelon la Banque mondiale, les villes africaines connaîtront un doublement de leur population en 2040 et un triplement en 2050 pour atteindre environ 1,5 milliards d'urbains (Lall, 2017). La dimension de ces prévisions donne toute sa mesure quand on les rapporte à l'espace dans lequel elles se réaliseront. Elles deviennent même très vite alarmantes, car aujourd'hui déjà, les villes d'Afrique subsaharienne n'arrivent pas à offri
Stéphane JoostExpertise
Geographic Information Science and spatial statisticsMolecular ecology, Landscape genomics, Seascape genomicsSpatial epidemiology, Health geographics
Publications Publications- List of publications
Teaching & PhD PhD Students Marco André Vieira Ruas, Manon Laetitia Pribille, Martine Valérie Besse Past EPFL PhD Students Estelle Rochat, Solange Catherine Gaillard, Oliver Michele Selmoni, Anaïs Ladoy, Annie Sandrine Guillaume Past EPFL PhD Students as codirector Sylvie Stucki, Kevin Leempoel, Martí
