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Concept

Subventricular zone

Related publications (24)

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

Pierre Magistretti, Igor Allaman

The energy demands of the brain are high: they account for at least 20% of the body's energy consumption. Evolutionary studies indicate that the emergence of higher cognitive functions in humans is associated with an increased glucose utilization and expre ...

Elsevier2015

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

Patrick Aebischer, Bernard Schneider, Cylia Cloé Rochat, Christopher Towne, Elisabeth Anne Dirren, Julianne Bobela

Objective: Amyotrophic lateral sclerosis is an incurable disorder mainly characterized by motoneuron degeneration. Mutations in the superoxide dismutase 1 (SOD1) gene account for 20% of familial forms of the disease. Mutant SOD1 exerts multiple pathogenic ...

Wiley-Blackwell2015

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes

Pierre Magistretti, Igor Allaman

There is growing evidence that astrocytes are involved in the neuropathology of major depression. In particular, decreases in glial cell density observed in the cerebral cortex of individuals with major depressive disorder are accompanied by a reduction of ...

Bentham Science Publishers2013

High-throughput clonal analysis of neural stem cells in microarrayed artificial niches

Matthias Lütolf, Samy Gobaa

To better understand the extrinsic signals that control neural stem cell (NSC) fate, here we applied a microwell array platform which allows high-throughput clonal analyses of NSCs, cultured either as neurospheres or as adherent clones, exposed to poly(eth ...

2012