Concept

Fluxional molecule

Related publications (15)

Synthesis and host-guest chemistry of molecular cages containing gold or zirconium

The kinetic inertness and low solubility of Au3(pyrazolate)3 complexes have made it difficult to integrate them into supramolecular assemblies. In this thesis, an investigation into the dynamic combinatorial chemistry of these complexes is presented, followed by strategies for their incorporation into molecular cages and a study of the host - guest chemistry of the resulting assemblies. The first research chapter, Chapter 2, describes the constitutional dynamic chemistry of Au3(pyrazolate)3 complexes. Liga

EPFL2026

Peptide/Protein Functionalization and Macrocyclization via Alkyne Umpolung with Hypervalent Iodine Reagents

Alkynes are one of the most fundamental functional groups in organic synthesis due to the versatile chemistry of the triple bond, their unique rigid structure, and their use in bioconjugation. The introduction of alkynes onto organic molecules traditionally relies on nucleophilic activation, often requiring strong bases or metal catalysts. These conditions, however, restrict applications involving biomolecules such as peptides and proteins due to functional group incompatibility. To address this limitation,

American Chemical Society2025

Carbon dioxide reduction by dinuclear Yb(ii) and Sm(ii) complexes supported by siloxide ligands

Marinella Mazzanti, Farzaneh Fadaei Tirani, Davide Toniolo

Two dinuclear homoleptic complexes of lanthanides(II) supported by the polydentate tris(tertbutoxy) siloxide ligand ([Yb2L4], 1-Yb and [Sm2L4], 1-Sm, (L = (OtBu)3SiO−)) were synthesized in 70–80% yield and 1-Sm was crystallographically characterized. 1-Yb ...

2019

Nanocomposites based on luminescent colloidal nanocrystals in polymers: new opportunities for micro and nano fabrication

Vahid Fakhfouri

In recent years a wide range of materials including metals, semiconductors and metal oxides have been synthesized with nanometer dimensions. In particular II–VI semiconductor nanocrystals (NCs) are receiving considerable attention for fundamental studies as zerodimensional quantum confined material and for their potential application in optoelectronics and photonics. The colour tunability of the emission of semiconductor NCs as a function of size is one of their most attractive properties. A current bottle-

2005

[CpRu((R)-Binop-F)(H2O)][SbF6], a New Fluxional Chiral Lewis Acid Catalyst: Synthesis, Dynamic NMR, Asymmetric Catalysis, and Theoretical Studies

André Merbach

The C2-sym. electron-poor ligand (R)-BINOP-F (4; (R)-2,2'-[bis(pentafluorophenyl)phosphinoxy]-1,1'-binaphthalene) was prepd. by reaction of (R)-BINOL ((R)-1,1'-binaphthalene-2,2'-diol) with bromobis(pentafluorophenyl)phosphine in the presence of NEt3. The iodo complex [CpRu((R)-BINOP-F)(I)] ((R)-6) was obtained by substitution of two carbonyl ligands by (R)-4 in the in situ-prepd. [CpRu(CO)2H] complex followed by reaction with iodoform. Complex 6 was reacted with [Ag(SbF6)] in acetone to yield [CpRu((R)-BIN

2004

Triple Quantum Decoherence under Multiple Refocusing: Slow Correlated Chemical Shift Modulations of C' and N Nuclei in Proteins

Geoffrey Bodenhausen, Dominique Früh

A new expt. allows the identification of residues that feature slow conformational exchange in macromols. Rotations about dihedral angles that are slower than the global correlation time tc cause a modulation of the isotropic chem. shifts of the nuclei. If these fluctuations are correlated they induce a differential line broadening between three-spin single-quantum and triple-quantum coherences involving three nuclei such as the carbonyl C', the neighboring amide nitrogen N and the amide proton HN belonging

2004

On the products obtained from reaction of rac-diphenyl[2.2]para-cyclophanylphosphine with (cycloocta-1,5-diene)palladium(II)chloride

The reaction of Pd(cod)Cl-2 (cod = cycloocta-1,5-diene) with 1 and 2 equiv. of rac-diphenyl[2.2]paracyclophanylphosphine, rac-PPh2(C16H15), affords the dimer Pd{PPh2(C16H15)}Cl-2 (1) and the square-planar complex trans-Pd{PPh2(C16H15)}(2)Cl-2 (2), respectively. In solution the dimer undergoes a fluxional process which has been probed by NMR and involves isomerisation between pseudo-trans- and cis-conformations. The structures of trans -Pd{Ph-2(C16H15)}Cl-2 (1a) and 2 have been established by singl

2003

Conformations of an amino-amido-thiolate self-assembled layer on gold in air and in electrolytes

Klaus Kern, Horst Arthur Vogel, Raymond Houriet, Maximilian Epple, Andreas Heusler

The amino-amido-thiol AT (HS-(CH2)10-CO-NH-CH2-CH2-NH2)(HS-(CH2)10-CO-NH-CH2-CH2-NH2), adsorbed on Au(111), was studied by sum frequency generation (SFG) and IR reflection absorption spectroscopy in the CH2 stretching vibration region. The SFG and IR spectra are qual. similar; both show the sym. stretching band and an intense and unusually broad antisym. stretching band. The IR spectra show a reversible difference between a sample dried after rinsing in electrolyte and dried after rinsing in ethanol, thus e

2003

First-principles electronic structure study of Ti-PTCDA contacts

Alfredo Pasquarello

We investigate the interaction of Ti atoms with thin films made of 3,4,9,10 perylenetetracarboxylic dianhydride (PTCDA) molecules by means of self-consistent electronic structure calculations within a generalized gradient approximated density-functional theory framework. Following experimental suggestions, we model the thin films in terms of the bulk crystallographic structure of PTCDA. We fully optimize the atomic PTCDA structures in the presence of Ti impurities by local minimizations of the electronic to

American Physical Society2002

Intramolecular dynamics of [Rh-4(CO)(6)(mu-PPh2)(4)] in solution

Gabor Laurenczy, Raymond Roulet

A Rh-103, P-31 and C-13 NMR study of [Rh-4(CO)(6)(mu-PPh2)(4)] in CD2Cl2 indicates that the strongly bonded, bridging, anionic ligand PPh2- takes part in the site exchange of the carbonyl ligands and is actually mobile about the metallic surface of this cluster compound.

2002

The reaction of alkynes with triangulo-clusters [Pt3(m-CO)3(PR3)3]

Gabor Laurenczy, Raymond Roulet

The reaction of the cluster complexes [Pt-3(mu -CO)(3)(PR3)(3)] (PR3 = PPh3 1, PPh(2)Bz 2, PCy3 3 and P(i)pr(3) 4) with dialkyl acetylenedicarboxylate, R'O2CC drop CCO2R' (R= CH3 or Bu-t) have been examined under various conditions. At low temperature the alkyne reacts quantitatively giving the unstable adducts [Pt-3(CO)(3)(PR3)(3)(mu (3)-alkyne)]. The stereochemistry of the intermediate [Pt-3(CO)(3)(PPh3)(3)(mu (3)-(BuO2CC)-Bu-t drop (CCO2Bu)-Bu-t)] 5has been deduced from low temperature Pt-195-{H-1}, P-31

2001

Can Octahedral t2g6 Complexes Substitute Associatively? The Case of the Isoelectronic Ruthenium(II) and Rhodium(III) Hexaaquaions

André Merbach, François Rotzinger

For the low-spin t2g6 Ru(OH2)62+ (ΔV⧧ = −0.4 cm3 mol-1) and Rh(OH2)63+ (ΔV⧧ = −4.2 cm3 mol-1) hexaaquaions, the respective Id and Ia water exchange mechanisms had been assigned, mainly on the basis of activation volumes ΔV⧧ and entering ligands effects for water substitution. For Ru(II) the near-zero ΔV⧧ was supposed to be due to the compensation between a positive contribution (the loss of a water molecule) and a negative one (the contraction of the bonds of the five spectator ligands at the transition sta

2000

Synthesis and 13C NMR study of the triangulo-clusters [Pt3(m-CO)3-n(m-SO2)n(PR3)3] (n = 0-3)

Gabor Laurenczy, Raymond Roulet

[Pt-3(mu-CO)(3)(PPh3)(3)] was prepared in high yield by the reaction of [Pt-3(mu-CO)(3)(PPh3)(4)] with H2O2. The carbonyl ligands in [Pt-3(mu-CO)(3)(PR3)(3)] (PR3 = PPh3, PPh(2)Bz, PCy3, P'Pr-3) may be completely replaced by sulfur dioxide to give [Pt-3(mu-SO2)(3)(PR3)(3)] or partially by one SO2 to give [Pt-3(mu-CO)(2)(mu-SO2)(PR3)(3)] (PR3 = PCy3 and (PPr3)-Pr-i). On the other hand, the addition of one molar equivalent of carbon monoxide to [Pt-3(mu-SO2)(3)(PR3)(3)] (PR3 = PCy3, (PPr3)-Pr-i) gave the comp

2000

Multiple timescales in the intramolecular vibrational energy redistribution of highly excited methanol

Highly resolved vibrational overtone spectra of jet-cooled CH3OH, obtained using selective IRLAPS detection of the vibrational transition, reveal rich vibrational structure that carries detailed information on the intramolecular dynamics. Low-resolution single resonance spectra of the jet-cooled molecules exhibit a 50 cm(-1) splitting resulting from strong coupling between the OH and CH stretch modes at the energy of the 5 nu(OH) band. Subsequent to coherent excitation, this coupling would lead to energy re

1995

Synthèse et dynamique intramoléculaire du cluster dodécacarbonyle triiridiumrhodium et de ses dérivés

The goal of our work was the synthesis and studies on the reactivity and intramolecular dynamics of new classes of mixed clusters of the type Ir3Rh(CO)12. In total 17 derivatives of this compound have been synthesized, with ligands such as halogenides, mono- and diolefines, diarsines, carbenes, sulphur ligands and phosphines. Consecutively 16 derivatives of Ir4(CO)12 and Ir2Rh2(CO)12 analogues have been prepared to determine the effect of d9 metal substitution on the nature and activation energies of the fl

EPFL1993

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Related publications (15)

[CpRu((R)-Binop-F)(H2O)][SbF6], a New Fluxional Chiral Lewis Acid Catalyst: Synthesis, Dynamic NMR, Asymmetric Catalysis, and Theoretical Studies

André Merbach

2004

Triple Quantum Decoherence under Multiple Refocusing: Slow Correlated Chemical Shift Modulations of C' and N Nuclei in Proteins

Geoffrey Bodenhausen, Dominique Früh

2004

On the products obtained from reaction of rac-diphenyl[2.2]para-cyclophanylphosphine with (cycloocta-1,5-diene)palladium(II)chloride

2003

Can Octahedral t2g6 Complexes Substitute Associatively? The Case of the Isoelectronic Ruthenium(II) and Rhodium(III) Hexaaquaions

André Merbach, François Rotzinger

2000