Giovanni Carlo CangianiExpertise
HPC, Algorithms, Networking, Programming, IT, Unix, DevOps, Full-stack Development, Computational Solid State Physics
Current work
Full stack developer and dev-ops engineer for the central IT services of EPFL.
Mission
See my daughters grow up and become graceful, kind, curious, cultivated, and literate.
Education Laurea | Computational solid state physics 1997 – 1997 Trieste Directed by Prof. Alfonso Baldereschi PhD | Computational solid state physic
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Paolo IennePaolo Ienne has been a Professor at the EPFL since 2000 and heads the Processor Architecture Laboratory (LAP). Prior to that, he worked for the Semiconductors Group of Siemens AG, Munich, Germany (which later became Infineon Technologies AG) where he was at the head of the Embedded Memories unit in the Design Libraries division. His research interests include various aspects of computer and processor architecture, FPGAs and reconfigurable computing, electronic design automation, and computer arithmetic. Ienne was a recipient of Best Paper Awards at the 20th, 24th, and 28th ACM/SIGDA International Symposia on Field-Programmable Gate Arrays (FPGA), in 2012, 2016 and 2020, at the 19th and 30th International Conference on Field-Programmable Logic and Applications (FPL), in 2009 and 2020, at the International Conference on Compilers, Architectures, and Synthesis for Embedded Systems (CASES), in 2007, and at the 40th Design Automation Conference (DAC), in 2003; many other papers have been candidates to Best Paper Awards in prestigious venues. He has served as general, programme, and topic chair of renown international conferences, including organizing in Lausanne the 26th International Conference on Field-Programmable Logic and Applications (FPL) in 2016. He serves on the steering committee of the IEEE Symposium on Computer Arithmetic (ARITH) and of the International Conference on Field-Programmable Logic and Applications (FPL). Ienne has guest edited a number of special issues and special sections on various topics for IEEE and ACM journals. He is regularly member of program committees of international workshops and conferences in the areas of design automation, computer architecture, embedded systems, compilers, FPGAs, and asynchronous design. He has been an associate editor of ACM Transactions on Architecture and Code Optimization (TACO), since 2015, of ACM Computing Surveys (CSUR), since 2014, and of ACM Transactions on Design Automation of Electronic Systems (TODAES) from 2011 to 2016.
Mario PaoloneMario Paolone received the M.Sc. (with honors) and the Ph.D. degree in electrical engineering from the University of Bologna, Italy, in 1998 and 2002, respectively. In 2005, he was appointed assistant professor in power systems at the University of Bologna where he was with the Power Systems laboratory until 2011. In 2010, he received the Associate Professor eligibility from the Politecnico di Milano, Italy. Since 2011 he joined the Swiss Federal Institute of Technology, Lausanne, Switzerland, where he is now Full Professor, Chair of the Distributed Electrical Systems laboratory and Head of the Swiss Competence Center for Energy Research (SCCER) FURIES (Future Swiss Electrical infrastructure). He was co-chairperson of the technical programme committees of the 9th edition of the International Conference of Power Systems Transients (IPST 2009) and of the 2016 Power Systems Computation Conference (PSCC 2016). He was chair of the technical programme committee of the 2018 Power Systems Computation Conference (PSCC 2018). In 2013, he was the recipient of the IEEE EMC Society Technical Achievement Award. He was co-author of several papers that received the following awards: best IEEE Transactions on EMC paper award for the year 2017, in 2014 best paper award at the 13th International Conference on Probabilistic Methods Applied to Power Systems, Durham, UK, in 2013 Basil Papadias best paper award at the 2013 IEEE PowerTech, Grenoble, France, in 2008 best paper award at the International Universities Power Engineering Conference (UPEC). He was the founder Editor-in-Chief of the Elsevier journal Sustainable Energy, Grids and Networks and was Associate Editor of the IEEE Transactions on Industrial Informatics. His research interests are in power systems with particular reference to real-time monitoring and operation, power system protections, power systems dynamics and power system transients. Mario Paolone is author or coauthor of over 300 scientific papers published in reviewed journals and international conferences.
Stephan BrunnerTeaching & PhD PhD Students Hugo Jean Elie Chkroun, Nicole Vadot, Oraz Anuaruly, Haomin Sun, Isabel Muzio, Fabien Nicolas Jeanquartier Past EPFL PhD Students Ajay Chandrarajan Jayalekshmi, Arnas Volcokas Past EPFL PhD Students as codirector Xavier Lapillonne, Thibaut Vernay, Julien Stanislas Pierre Dominski, Gabriele Merlo, Emmanuel Lanti, Noé Ohana, Moahan Murugappan Courses Plasma instabilities PHYS-736 To complete the theoretical knowledge acquired before the graduate studies.
Pascal FrossardTeaching & PhD PhD Students Yiming Qin, Alba Carballo Castro, Elisa Messori, Ke Wang, Sevda Ögüt, Tuna Alikasifoglu, William Cappelletti, Manuel Madeira, Mahdi Amiri, Ortal Yona Senouf, Vasiliki Rizou, Cem Bilaloglu, Abdellah Rahmani, Amel Abdelraheem, Jérémy Jean Philippe Baffou, Adam Hazimeh, Vincent Jung, Yike Zhao Past EPFL PhD Students Dan Jurca, Jean-Paul Wagner, Ivana Radulovic, Ivana Tosic, Effrosyni Kokiopoulou, Zafer Arican, Vijayaraghavan Thirumalai, Tamara Tosic, Eirina Bourtsoulatze, Elif Vur
Coralie BussoExpériences professionnelles Apprentie Laborantine 2001–2004 CMU Dpt. de physiologie cellulaire et métabolisme
RechercheCentrosomes promote timely mitotic entry in C. ele Dev Cell. 2007 Apr;12(4):531-41.Centrosomes promote timely mitotic entry in C. elegans embryos.Hachet V, Canard C, Gönczy P.SourceSwiss Institute for Experimental Cancer Research (ISREC), and School of Life Sciences, Swiss Federal Institute of Technology (EPFL), CH-1066 Lausanne, Switzerland.AbstractSeveral mitotic regulators, including
Roger HerschRoger D. Hersch is professor of Computer Science and head of the Peripheral Systems Laboratory at EPFL. He received his engineering degree from ETHZ in 1975, worked in industry from 1975 to 1980, and obtained his PhD degree from EPFL in 1985. He directed the widely known
Visible Human Web Server project
, which offers a number of services for the visualization of human anatomy.
His current research focuses on color reproduction, spectral color prediction models, moiré imaging, and visual document security. Recent achievements include the PhotoProtect technology, which incorporates text as chromatic differences in order to protect identity photographs (Swiss driving license), microstructure imaging, which is used by railways companies (SNCF, RENFE) and festival organizers (Paleo) to print tickets at home and the band moire imaging technology for the protection of security documents.
Babak FalsafiBabak is a Professor in the School of Computer and Communication Sciences and the founding director of the EcoCloud, an industrial/academic consortium at EPFL investigating scalable data-centric technologies. He has made numerous contributions to computer system design and evaluation including a scalable multiprocessor architecture which was prototyped by Sun Microsystems (now Oracle), snoop filters and memory streaming technologies that are incorporated into IBM BlueGene/P and Q and ARM cores, and computer system performance evaluation methodologies that have been in use by AMD, HP and Google PerKit . He has shown that hardware memory consistency models are neither necessary (in the 90's) nor sufficient (a decade later) to achieve high performance in multiprocessor systems. These results eventually led to fence speculation in modern microprocessors. His latest work on workload-optimized server processors laid the foundation for the first generation of Cavium ARM server CPUs, ThunderX. He is a recipient of an NSF CAREER award, IBM Faculty Partnership Awards, and an Alfred P. Sloan Research Fellowship. He is a fellow of IEEE and ACM.
Pierre VandergheynstPierre Vandergheynst received the M.S. degree in physics and the Ph.D. degree in mathematical physics from the Université catholique de Louvain, Louvain-la-Neuve, Belgium, in 1995 and 1998, respectively. From 1998 to 2001, he was a Postdoctoral Researcher with the Signal Processing Laboratory, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland. He was Assistant Professor at EPFL (2002-2007), where he is now a Full Professor of Electrical Engineering and, by courtesy, of Computer and Communication Sciences. As of 2015, Prof. Vandergheynst serves as EPFL’s Vice-Provost for Education. His research focuses on harmonic analysis, sparse approximations and mathematical data processing in general with applications covering signal, image and high dimensional data processing, computer vision, machine learning, data science and graph-based data processing. He was co-Editor-in-Chief of Signal Processing (2002-2006), Associate Editor of the IEEE Transactions on Signal Processing (2007-2011), the flagship journal of the signal processing community and currently serves as Associate Editor of Computer Vision and Image Understanding and SIAM Imaging Sciences. He has been on the Technical Committee of various conferences, serves on the steering committee of the SPARS workshop and was co-General Chairman of the EUSIPCO 2008 conference. Pierre Vandergheynst is the author or co-author of more than 70 journal papers, one monograph and several book chapters. He has received two IEEE best paper awards. Professor Vandergheynst is a laureate of the Apple 2007 ARTS award and of the 2009-2010 De Boelpaepe prize of the Royal Academy of Sciences of Belgium.
David Atienza AlonsoDavid Atienza Alonso is an associate professor of EE and director of the Embedded Systems Laboratory (ESL) at EPFL, Switzerland. He received his MSc and PhD degrees in computer science and engineering from UCM, Spain, and IMEC, Belgium, in 2001 and 2005, respectively. His research interests include system-level design methodologies for multi-processor system-on-chip (MPSoC) servers and edge AI architectures. Dr. Atienza has co-authored more than 350 papers, one book, and 12 patents in these previous areas. He has also received several recognitions and award, among them, the ICCAD 10-Year Retrospective Most Influential Paper Award in 2020, Design Automation Conference (DAC) Under-40 Innovators Award in 2018, the IEEE TCCPS Mid-Career Award in 2018, an ERC Consolidator Grant in 2016, the IEEE CEDA Early Career Award in 2013, the ACM SIGDA Outstanding New Faculty Award in 2012, and a Faculty Award from Sun Labs at Oracle in 2011. He has also earned two best paper awards at the VLSI-SoC 2009 and CST-HPCS 2012 conference, and five best paper award nominations at the DAC 2013, DATE 2013, WEHA-HPCS 2010, ICCAD 2006, and DAC 2004 conferences. He serves or has served as associate editor of IEEE Trans. on Computers (TC), IEEE Design & Test of Computers (D&T), IEEE Trans. on CAD (T-CAD), IEEE Transactions on Sustainable Computing (T-SUSC), and Elsevier Integration. He was the Technical Program Chair of DATE 2015 and General Chair of DATE 2017. He served as President of IEEE CEDA in the period 2018-2019 and was GOLD member of the Board of Governors of IEEE CASS from 2010 to 2012. He is a Distinguished Member of ACM and an IEEE Fellow.
Henning Paul-Julius StahlbergMission
We use high-resolution cryo-electron microscopy to study neurodegeneration and other protein systems. We also develop novel imaging technology in the areas of electron microscopy hardware and applications, sample preparation, data collection schemes, and data analysis software systems. The Stahlberg group is supported by the University of Lausanne, Faculty of Medicine and Biology, and by the EPFL, Faculty of Basic Sciences, Physics Institute. The LBEM is a research laboratory of both UNIL and EPFL.
