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Related publications (33)

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Acute and Long-Term Effects of Aortic Compliance Decrease on Central Hemodynamics: A Modeling Analysis

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Stamatia Zoi Pagoulatou

Aortic compliance is an important determinant of cardiac afterload and a contributor to cardiovascular morbidity. In the present study, we sought to provide in silico insights into the acute as well as long-term effects of aortic compliance decrease on cen ...

FRONTIERS MEDIA SA2021

The effect of left ventricular contractility on arterial hemodynamics: A model-based investigation

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Stamatia Zoi Pagoulatou

Ventricular-arterial coupling is a major determinant of cardiovascular performance, however, there are still inherent difficulties in distinguishing ventricular from vascular effects on arterial pulse phenotypes. In the present study, we employed an extens ...

2021

Feasibility of a Dielectric Elastomer Augmented Aorta

Yves Perriard, Yoan René Cyrille Civet, Jonathan André Jean-Marie Chavanne, Morgan Almanza, Francesco Clavica, David Moser

Although heart transplantation is a gold standard for severe heart failure, there is a need for alternative effective therapies. A dielectric‐elastomer aorta is used to augment the physiological role of the aorta in the human circulatory system. To this en ...

2021

In vivo application and validation of a novel noninvasive method to estimate the end-systolic elastance

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Stamatia Zoi Pagoulatou

Accurate assessment of the left ventricular (LV) systolic function is indispensable in the clinic. However, estimation of a precise index of cardiac contractility, i.e., the end-systolic elastance (E-es), is invasive and cannot be established as clinical r ...

2021

Energy Analysis of a Cardiac Assist Device based on Dielectric Elastomer Actuator through an Equivalent Electrical Circuit

Yves Perriard, Yoan René Cyrille Civet, Jonathan André Jean-Marie Chavanne, Francesco Clavica

Lumped parameter model and mock circulation loop are two tools commonly used in biomedical research to simulate cardiac system in order to study different assist devices. In this paper, a lumped parameter model is proposed to simulate a circulation loop. T ...

IEEE2021

FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure

Mauro Delorenzi, Alexis Rapin, Dominique Velin

The mechanisms maintaining adult lymphatic vascular specialization throughout life and their role in coordinating inter-organ communication to sustain homeostasis remain elusive. We report that inactivation of the mechanosensitive transcription factor Foxc ...

AMER ASSOC ADVANCEMENT SCIENCE2021

Non-invasive monitoring of key hemodynamical and cardiac parameters using physics-based modelling and artificial intelligence

Vasiliki Bikia

In a progressively aging population, it is of utmost importance to develop reliable, non-invasive, and cost-effective tools to estimate biomarkers that can be indicative of cardiovascular risk. Clinical parameters directly measured in the heart or the aort ...

EPFL2021

Method and system for determining the intention of performing a voluntary action

Olaf Blanke, Oliver Alan Kannape, Hyeongdong Park, Bastien Orset

The invention relates to methods and systems for determining the intention of a subject to perform a voluntary action based on the analysis of the subject's respiratory phases and neuroelectrical signals. ...

2021

On the assessment of arterial compliance from carotid pressure waveform

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Stamatia Zoi Pagoulatou

In a progressively aging population, it is of utmost importance to develop reliable, noninvasive, and cost-effective tools to estimate biomarkers that can be indicative of cardiovascular risk. Various pathophysiological conditions are associated to changes ...

AMER PHYSIOLOGICAL SOC2021

CNN-Based Ultrasound Image Reconstruction for Ultrafast Displacement Tracking

Jean-Philippe Thiran, Dimitris Perdios, Marcel Arditi, Florian Martinez, Manuel Vonlanthen

Thanks to its capability of acquiring full-view frames at multiple kilohertz, ultrafast ultrasound imaging unlocked the analysis of rapidly changing physical phenomena in the human body, with pioneering applications such as ultrasensitive flow imaging in t ...

Institute of Electrical and Electronics Engineers2021

Method and system for generating a three-dimensional model based on spherical photogrammetry

Frédéric Kaplan, Pierre-André Mudry, Nils Hamel, Albane Bénédicte Descombes

A computer-implemented method is proposed for creating a three-dimensional model of the environment. The method comprises the steps of planning (105) a trajectory for a moving system carrying an omnidirectional camera comprising a first image sensor facing ...

2021

System and methods for differential imaging using a lock-in camera

Christophe Moser, Damien Claude-Marie Loterie, Timothé Laforest, Chiara Bonati

The present invention describes an imaging system that allows visualization of a wide range of samples both in terms of morphology and in terms of material (e.g. density distribution, varying chemical composition, or anything that induces a change of optic ...

2021

Smart Portable Pen for Continuous Monitoring of Anaesthetics in Human Serum With Machine Learning

Sandro Carrara, Danilo Demarchi, Simone Aiassa, Mandresy Ivan Ny Hanitra

Continuous monitoring of anaesthetics infusion is demanded by anaesthesiologists to help in defining personalized dose, hence reducing risks and side effects. We propose the first piece of technology tailored explicitly to close the loop between anaesthesi ...

2021