Analyzes a mutant DDX3 enzyme's ATPase activity and inhibitor development, covering RNA chaperones, crystal structures, and mass spectrometry-based protein profiling.
Explores biology fundamentals, proteins, lipids, and DNA as synthetic materials, covering cell structure, membrane composition, protein production, DNA structure, and tissue engineering.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.