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Concept

Phospholipid scramblase

Related publications (26)

Formation and study of single metal ion–phospholipid complexes in biphasic electrospray ionization mass spectrometry

Hubert Girault, Anne-Clémence Corminboeuf, Manuel Alejandro Méndez Agudelo, Michel Prudent, Daniel Filipe Dos Santos Alves Jana

Single metal ion-phospholipid complexes are observed in biphasic electrospray ionization mass spectrometry (BESI-MS) using a dual-channel microsprayer. Such a microsprayer makes it possible to put into contact two immiscible liquids within the Taylor cone. ...

Royal Society of Chemistry2010

The dynamics of cardiolipin synthesis post-mitochondrial fusion

Richardus Houtkooper

Alteration in mitochondrial fusion may regulate mitochondrial metabolism. Since the phospholipid cardiolipin (CL) is required for function of the mitochondrial respiratory chain, we examined the dynamics of CL synthesis in growing Hela cells immediately af ...

2010

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

Richardus Houtkooper

The BH3-only BID (BH3-interacting domain death agonist) protein has a critical function in the death-receptor pathway in the liver by triggering mitochondrial outer membrane permeabilization (MOMP). Here we show that MTCH2/MIMP (mitochondrial carrier homol ...

2010

The enigmatic role of tafazzin in cardiolipin metabolism

Richardus Houtkooper

The mitochondrial phospholipid cardiolipin plays an important role in cellular metabolism as exemplified by its involvement in mitochondrial energy production and apoptosis. Following its biosynthesis, cardiolipin is actively remodeled to achieve its final ...

2009

Peptide-Phospholipid Complex Formation at Liquid-Liquid Interfaces

Hubert Girault, Bin Su, Manuel Alejandro Méndez Agudelo, Michel Prudent

Two peptides known to interact with receptors embedded in cell membranes, angiotensin III (AngIII) and Leuenkephalin(LeuEnk), were studied electrochemically at the interface formed between two immiscible electrolyte solutions modified by an adsorbed monola ...

2008

Chemical Mapping of Ceramide Distribution in Sphingomyelin-Rich Domains in Monolayers

Dusan Vobornik

The incorporation of ceramide in phase-separated monolayers of ternary lipid mixtures has been studied by a combination of atomic force microscopy (AFM), fluorescence, and time-of-flight secondary ion mass spectrometry (ToF-SIMS). Replacement of a fraction ...

American Chemical Society2008