Jean-Paul Richard KneibExpertise
Cosmology, Gravitational Lensing, Redshift Survey, First Galaxies, Cluster of Galaxies, Fiber-positioner robotic system, Radio Astronomy, Space Sustainibility
Current work
- Former Principal investigator of the SDSS-IV eBOSS project. This is an international project assembling more than 150 participants located mainly in Europe, USA and China. This project will observe 1.5 million galaxy and quasars over 2014-2020 to accurately measure the expansion history of the Universe. * Member of the DESI co
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Stefano CodaTeaching & PhD PhD Students Vincent Masson, Luigi Persico, Ewout Koen L. Devlaminck, Martino Bonisolli, Alessandro Balestri, Mackenzie Peter-Fulford Van Rossem, James Winston Irawati Tumbokon, Salomon Guinchard, Inès Vergara, Michele Bottino Past EPFL PhD Students Alessandro Marinoni, Silvano Gnesin, Cornelis Adrianus de Meijere, Josef Kamleitner, Zhouji Huang, Himank Anand, Pedro Andres Molina Cabrera, Dahye Choi, Federico Pesamosca, Aylwin Iantchenko, Jean Arthur Cazabonne
Yves MartinTeaching & PhD Past EPFL PhD Students as codirector Francesco Piras, Jonathan Rossel Courses Fusion and industrial plasma technologies PHYS-632 The course provides an overview of the technologies that are essential for fusion developments and for industrial plasmaapplications, highlighting the synergies between the two fields. The aim is to provide a combined theoretical andexperimental background to the various topics.
Olivier SauterTeaching & PhD PhD Students Cassandre Ekta Contré, Antonia Frank, Peizheng Zhang, Jean-Pierre Thomas Svantner, Cristina Venturini, Cosmas Quirin Lorenz Heiss, Daniel Perales Rios, Viacheslav Bochkarev, Jan Jakub Frybes, Paul Véronique Guillaume Devianne Past EPFL PhD Students Clemente Angioni, Petri Nikkola, Alberto Bottino, Andrei Martynov, Emiliano Fable, Costanza Zucca, Federico Felici, Dávid Wágner, Doohyun Kim, Anna Teplukhina, Mengdi Kong, Francesco Carpanese, Simon Van Mulders, Stefano Marchioni, F
Duccio TestaProfessionals experiences Supply teacher of mathematics, physics and computing 1994–1995 various high schools in Torino (Italy)
Teaching & PhD Past EPFL PhD Students as codirector Theodoros Panis, Lorenzo Stipani Courses Sustainable energy innovation HUM-292 This course provides an introduction to the technical, social, and economic fundamentals of energy. The course examines the concrete case of nuclear fusion. How could this energy reshape our world? How can we ensure its acceptability, st
Wulfram GerstnerWulfram Gerstner is Director of the Laboratory of Computational Neuroscience LCN at the EPFL. His research in computational neuroscience concentrates on models of spiking neurons and spike-timing dependent plasticity, on the problem of neuronal coding in single neurons and populations, as well as on the link between biologically plausible learning rules and behavioral manifestations of learning. He teaches courses for Physicists, Computer Scientists, Mathematicians, and Life Scientists at the EPFL. After studies of Physics in Tübingen and at the Ludwig-Maximilians-University Munich (Master 1989), Wulfram Gerstner spent a year as a visiting researcher in Berkeley. He received his PhD in theoretical physics from the Technical University Munich in 1993 with a thesis on associative memory and dynamics in networks of spiking neurons. After short postdoctoral stays at Brandeis University and the Technical University of Munich, he joined the EPFL in 1996 as assistant professor. Promoted to Associate Professor with tenure in February 2001, he is since August 2006 a full professor with double appointment in the School of Computer and Communication Sciences and the School of Life Sciences. Wulfram Gerstner has been invited speaker at numerous international conferences and workshops. He has served on the editorial board of the Journal of Neuroscience, Network: Computation in Neural Systems', Journal of Computational Neuroscience', and `Science'.
Jonathan GravesProf. Jonathan P. Graves is a Senior Scientist at EPFL and Honorary Visiting Professor at the University of York, UK. He achieved first class joint honours in Electronic Engineering and Mathematics from the University of Nottingham, UK in 1996. He completed his Ph.D. in Theoretical Mechanics from the University of Nottingham, UK, three years later in 1999. During his Ph.D. he was based in the Culham theory group of the United Kingdom Atomic Energy Authority, developing kinetic descriptions of the internal kink instability, and participating in deuterium-tritium experimental analysis in the Joint European Torus. After a short time in industry, and a postdoc at Nottingham University, he took a position at the Swiss Plasma Center at EPFL, becoming a Senior Scientist in 2014, and became an Honorary Visiting Professor at the University of York, UK, in 2020. In 2015 he became a member of the EUROfusion Scientific and Technical Advisory Committee (STAC) and a member of the EUROfusion DEMO Technical Advisory Group. He is on the editorial board for the journal Plasma Physics and Controlled Fusion, and in 2020 became Scientific Secretary of the Varenna-Lausanne International Workshop in Theory of Fusion Plasmas.
Stephan MorgenthalerACADEMIC POSITIONS
Professor of Applied Statistics, EPFL, 1988-present
Associate Professor of Statistics, Yale University, 1987-1988
Assistant Professor of Statistics, Yale University, 1983-1987
Instructor of Mathematics, Massachusetts Institute of Technology, 1983-1984
Cristian GalpertiExpertise
Control systems design and commissioning, especially involving complex scientific research architectures. Electronics engineering, embedded systems design and programming. Mechanical engineering, servo actuator systems design and commissioning.
Current Work
In charge of the direction of the control systems service of the Swiss Plasma Center
Education Ph.D. in Computer Science | 2005 – 2009 Politecnico di Milano Master degree in Electronics Engineering | 1998
David Atienza AlonsoDavid Atienza Alonso is an associate professor of EE and director of the Embedded Systems Laboratory (ESL) at EPFL, Switzerland. He received his MSc and PhD degrees in computer science and engineering from UCM, Spain, and IMEC, Belgium, in 2001 and 2005, respectively. His research interests include system-level design methodologies for multi-processor system-on-chip (MPSoC) servers and edge AI architectures. Dr. Atienza has co-authored more than 350 papers, one book, and 12 patents in these previous areas. He has also received several recognitions and award, among them, the ICCAD 10-Year Retrospective Most Influential Paper Award in 2020, Design Automation Conference (DAC) Under-40 Innovators Award in 2018, the IEEE TCCPS Mid-Career Award in 2018, an ERC Consolidator Grant in 2016, the IEEE CEDA Early Career Award in 2013, the ACM SIGDA Outstanding New Faculty Award in 2012, and a Faculty Award from Sun Labs at Oracle in 2011. He has also earned two best paper awards at the VLSI-SoC 2009 and CST-HPCS 2012 conference, and five best paper award nominations at the DAC 2013, DATE 2013, WEHA-HPCS 2010, ICCAD 2006, and DAC 2004 conferences. He serves or has served as associate editor of IEEE Trans. on Computers (TC), IEEE Design & Test of Computers (D&T), IEEE Trans. on CAD (T-CAD), IEEE Transactions on Sustainable Computing (T-SUSC), and Elsevier Integration. He was the Technical Program Chair of DATE 2015 and General Chair of DATE 2017. He served as President of IEEE CEDA in the period 2018-2019 and was GOLD member of the Board of Governors of IEEE CASS from 2010 to 2012. He is a Distinguished Member of ACM and an IEEE Fellow.
Ambrogio FasoliAmbrogio FASOLI was born on November 10, 1964, in Milano, Italy. After a classical high school diploma (Maturità Classica) and graduation from the University of Milano, with the degree of Dottore in Fisica, he obtained his Phd at the Ecole Polytechnique Fédérale (EPFL) with a thesis on chaos in wave-particle interactions in plasmas, which was awarded the Best EPFL Thesis prize, in 1993. He then moved to the JET Joint Undertaking, the largest worlds fusion device, near Oxford, UK, to investigate Alfvén waves and burning plasma physics. In 1995-1996 he took a sabbatical leave, visiting several Universities and Research Institutes in Europe and in the USA, including three months at General Atomics in San Diego. In 1996-1997, during a second period at JET, he participated in the fusion power worlds record experiments in Deuterium-Tritium plasmas at JET. In 1997 he was nominated Assistant Professor in MIT Physics Department, where he led a basic plasma physics group and the international collaboration between MIT and JET. In 2001 Ambrogio FASOLI was nominated Assistant Professor of Physics at EPFL, Lausanne, Switzerland, and Professeur Boursier of the Swiss National Science Foundation. He became member of CRPP Directorate and took the leadership of CRPP basic plasma physics group and of the TCV tokamak, one of the major fusion experiments worldwide. At European level he was scientific coordinator for JET experiments, spokesperson for multi-machine experiments in the frame of International Tokamak Physics Activities, and Project Leader for a JET Enhancement project. In 2005 he became Associate Professor of Physics with tenure at EPFL, then member of EFDA Science and Technology Advisory Committee, and of the Steering Committee of the Association EURATOM-Swiss Confederation. From 2006 he was also Deputy Director, then from 2007 Executive Director of CRPP and from 2008 Full Professor of Physics at EPFL. For a number of years he was the Chair of the EPFL Physics Strategic Committee and a member of the Directorate of the EPFL School of Sciences. Since the summer of 2014 Professor FASOLI was the sole Director of CRPP. He now represents Switzerland in the EUROfusion General Assembly and Bureau, and in the Governing Board for Fusion for Energy. He is member of the EUROfusion DEMO project Board, of the Scientific Board of the Helmotz Virtual Institute on Advanced Microwave Diagnostics, of the European Delegation for the Cooperation between Euratom and the Government of India in Fusion Energy Research, of the European Consortium for the development of the ITER gyratron (EGYC), and participates to numerous international review panels. He chairs the FuseNet Academic Council, the International Advisory Panel for the Laboratory of Excellence Plas@Par in the Sorbonne Universities, the European Consortium for the construction of the ITER microwave Upper Launcher (ECHUL), and the Promotion Committee of the EPFL Faculty of Basic Sciences. He is one the three European representatives in the International Tokamak Physics Activities Coordinating Committee, advising ITER, and the Editor-in-Chief of the IAEA journal Nuclear Fusion. Since January 2019, Ambrogio Fasoli is the Chair of the General Assembly, i.e. the president of EUROfusion, the European Consortium for Development of Fusion Energy. Professor FASOLI is a Fellow of the American Physical Society and since 2001 a Visiting Professor at MIT Physics Department. He is the Director of the Swiss Plasma Center.
Michaela HirschmannTeaching & PhD PhD Students Patrick Hirling, Jonathan Petersson, Lucie Scharré Courses Astrophysics III : galaxy formation and evolution PHYS-465 Galaxy formation & evolution is about studying how galaxies in our Universe come into existence, how they evolve and what shapes their properties. This course describes the observational facts of galaxies and the various processes of galaxy evolution as seen from theoretical/numerical models. General physics : thermodynamics (English) P
Christoph BostedtTeaching & PhD PhD Students Eloisa Florence Manetti, Wenyi Jiang, Hankai Zhang, Loïc Lucien Cédric Bassement, Silas Strebel, Eliot Jermann Past EPFL PhD Students Jonas Knurr, Ningchen Yang Courses Optical methods in chemistry CH-417 Introduction and application of photon based tools for chemical sciences: from basic concepts to optical and x-ray lasers Physical Chemistry Seminar 1: Trends CH-643 Students can learn about the broader research in Phyiscal Chemistry and broaden