Charlotte SchaebenTeaching & PhD Courses Urban habitat and developement AR-465 Focusing on the forms of habitat of the most disadvantaged in the countries of the South and the North and the contexts of crises, in particular emergency architecture, the course offers a critical analysis of the urbanisation of the world in the 21st century.
Jean-Paul Richard KneibExpertise
Cosmology, Gravitational Lensing, Redshift Survey, First Galaxies, Cluster of Galaxies, Fiber-positioner robotic system, Radio Astronomy, Space Sustainibility
Current work
- Former Principal investigator of the SDSS-IV eBOSS project. This is an international project assembling more than 150 participants located mainly in Europe, USA and China. This project will observe 1.5 million galaxy and quasars over 2014-2020 to accurately measure the expansion history of the Universe. * Member of the DESI co
Frédéric MilaExpertise
Condensed matter theory, strongly correlated systems, frustrated and quantum magnetism, tensor networks
Mission
Perform research in condensed matter theory, whenever possible in collaboration with experimentalists at EPFL and throughout the world
Current Work
- Magnetism on the Shastry-Sutherland lattice- Tensor network approach to 2D strongly correlated systems- Thermal properties of 2D frustrated quantum magnets- Exotic phases of quantum one-dimensional models
Since 2003 Full Professor at EPFL (
Jack Richard GreenwoodExpertise
Superconducting magnets for fusion energy (LTS and HTS).Superconducting magnet technology prototyping and testing.High-field measurements on superconductors with currents up to 100 kA.Critical currents in superconducting materials: flux pinning, Josephson junctions, and percolation theory. Beyond (p,q) models.Superconductors under strain.
Current Work
I joined the Swiss Plasma Centre's Superconductivity Group (SPC-SG) in 2023. The group is part of EPFL and it is physically located at the Paul Sche
Valentin Daniel Maurice BourdonValentin Bourdon is an architect, postdoctoral researcher and teaching assistant. He obtained the french architectural diploma in 2013 from the École d’Architecture de la Ville et des Territoires Paris-Est at Marne-la-Vallée under the direction of Jacques Lucan, and completed his PhD at EPFL in 2020, under the supervision of Luca Ortelli. Since September 2021, he coordinates the Habitat Research Center at EPFL. Involved in the studies of the Laboratory of Construction and Conservation between 2017 and 2021, he also contributes in the supervision of its Housing Studio - Project Theory and Criticism for architecture bachelor. During his doctoral research, he benefited of an academic stay at Metrolab Brussels in 2019 with the support of the SNSF, and published multiple scientific and non-academic publications. His arrival in Switzerland and return to the academic world take place after a thorough professional experience in the parisian office MGAU Michel Guthmann Architecture Urbanisme. From 2010 to 2016, he participed to the majority of its developed projects and supervised several of them, both collective dwellings projects and urban projects.
Mathias LerchAss. Prof. Mathias Lerch heads the Urban Demography Laboratory (URBDEMO) at the Faculty of Natural, Architectural and Build Environment (ENAC), Ecole polytechnique fédérale de Lausanne (EPFL). To improve understanding of urban population growth, Lerch has developed multi-disciplinary research interests in the components of demographic change (mortality/health, fertility and migration), as well as in their interactions with socioeconomic and environmental developments.
Before joining the EPFL, Lerch has acted as the deputy head of the Laboratory of Fertility and Well-Being at the Max Planck Institute for Demographic Research. He has analyzed and taught population change at various Swiss and German universities, as well as at statistical offices, often in transition countries. Since 2008, he has regularly advised national governments, United Nations entities, survey programs and NGOs on population issues and data collection.
Stéphane JoostExpertise
Geographic Information Science and spatial statisticsMolecular ecology, Landscape genomics, Seascape genomicsSpatial epidemiology, Health geographics
Publications Publications- List of publications
Teaching & PhD PhD Students Marco André Vieira Ruas, Manon Laetitia Pribille, Martine Valérie Besse Past EPFL PhD Students Estelle Rochat, Solange Catherine Gaillard, Oliver Michele Selmoni, Anaïs Ladoy, Annie Sandrine Guillaume Past EPFL PhD Students as codirector Sylvie Stucki, Kevin Leempoel, Martí
Paola ViganòTeaching & PhD PhD Students Noélie Marion Charlotte Lecoanet, Shyam Sunder Sirimalla Past EPFL PhD Students Roberto Sega, Antoine Vialle, Tommaso Pietropolli, Sylvie Tram Nguyen, Anna Karla De Almeida Milani, Elena Calafati, Flore Jeanne Marie Andrea Guichot Courses Hidden rivers PENS-219 Hidden Rivers aims at fulfilling the need for an interdisciplinary understanding of the problematics surrounding urban streams, through ecological, hydrological, and spatial relationships found in riversc
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Solaiman Shokur2019 - now : Senior Scientist, Translational neuroengineering Laboratory, EPFL(Geneva)
Team leader: CHRONOS project, a multi-center European project that aims at developing the first chronically implanted prosthetic hand for transradial amputee patients with bidirectional communication capabilities. NCCR Robotics: Bi-directional control of supernumerary limbs.2014-2019: Research Coordinator, AASDAP (São Paulo, Brazil) Responsible for both the scientific production and the clinical protocol at the AASDAP neurorehabilitation laboratory.
2013-2014: Postdoctoral associate, Walk again project, Insituto Santos Dumond. (Natal, RN, Brazil)Head of the engineering team in charge of the system integration. 2010-2012: Visiting scientist, Nicolelis Lab (Duke University).
Development and validation of a virtual-reality based brain-machine interface for rhesus monkeys.
2007 – 2010: Teaching assistant, Laboratory of Robotics Systems (EPFL)
