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Concept

Mole (unit)

Related publications (12)

Discovery of macrocyclic inhibitors of challenging protein-protein interactions

Edward Jeffrey Will

Macrocycles are a therapeutic modality of interest for drugging challenging disease targets due to their high binding affinity and membrane permeability, enabling the discovery of orally delivered and efficacious therapeutics. Recent methods have enabled t ...

EPFL2024

Multipulsed Millisecond Ozone Gasification for Predictable Tuning of Nucleation and Nucleation-Decoupled Nanopore Expansion in Graphene for Carbon Capture

Kumar Varoon Agrawal, Mounir Driss Mensi, Luis Francisco Villalobos Vazquez de la Parra, Shiqi Huang, Mostapha Dakhchoune, Heng-Yu Chi, Kuang-Jung Hsu, Guangwei He, Wan-Chi Lee

Predictable and tunable etching of angstrom-scale nanopores in single-layer graphene (SLG) can allow one to realize high-performance gas separation even from similar-sized molecules. We advance toward this goal by developing two etching regimes for SLG whe ...

2021

Universal noise in continuous transport measurements of interacting fermions

Jean-Philippe Brantut

We propose and analyze continuous measurements of atom number and atomic currents using dispersive probing in an optical cavity. For an atom-number measurement in a closed system, we relate both the detection noise and the heating rate due to measurement b ...

2018

Mechanism of formation of silver nanoparticles in MAG-DMAEMA copolymer aqueous solutions

Philippe Buffat, Elena Suvorova Buffat

Dispersed Ag nanoparticles were prepared in aqueous solutions in the presence of pure poly[2-(dimethylamino)ethyl methacrylate] (poly-DMAEMA), poly[2-deoxy-2-methacrylamido-d-glucose] (poly-MAG), and their copolymers of poly[MAG–DMAEMA] with different mole ...

Springer Verlag2015

Variant and Invariant States for Reaction Systems

Dominique Bonvin, Julien Léo Billeter, Sriniketh Srinivasan

Models of chemical reactors can be quite complex as they include information regarding the reactions, the transfer of species between phases, the transfer of energy, and the inlet and outlet flows. Furthermore, the effects of the various phenomena are quit ...

2013

Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions

Florian Maria Wurm, Gaurav Backliwal, Sébastien Chenuet, Sarah Wulhfard

Transient transfection allows for fast production of recombinant proteins. However, the current bottlenecks in transient transfection are low titers and low specific productivity compared to stable cell lines. Here, we report an improved transient transfec ...

2008

Direct Observation of Microscopic Solvation at the Surface of Clusters by Ultrafast Photoelectron Imaging

Majed Chergui, Alejandro Gonzalez Gonzalez

We report on microscopic observation of solvation by argon atoms of excited states of an ethylenic-like mol., TDMAE (tetrakis dimethylaminoethylene). Two exptl. methods were used: gas phase dynamics for the observation of the evolution through excited stat ...

2008

Dispersion polymerization of methyl methacrylate in supercritical carbon dioxide: control of molecular weight distribution by adjusting particle surface area

Thierry Meyer

Expts. of Me methacrylate dispersion polymn. are carried out in a reaction calorimeter using PDMS-mMA (methacrylate-terminated polydimethylsiloxane) as surfactant. Different stabilizer concns. from 0 to 10 wt% with respect to monomer have been considered i ...

2007

A sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticles

Melody Swartz

Effective interstitial transport of particles is necessary for injected drug/diagnostic agents to reach the intended target; however, quantitative methods to estimate such transport parameters are lacking. In this study we develop an in vivo model for eval ...

2006

Positively Charged GdIII Cryptates: Slow, Associative Water Exchange

André Merbach, Lothar Helm

A combined variable-temp. and multiple field 17O NMR, EPR and NMRD study was performed for the 1st time on Gd(III) complexes of cryptand ligands, L1 and L2, where L1 contains three 2,2'-bipyridine units ([bpy.bpy.bpy]) and L2 is the disubstituted Me ester ...

2006

Fluorescence and phosphorescence from individual C-60 molecules excited by local electron tunneling

Majed Chergui, Wolf-Dieter Schneider, François Patthey, Marina Pivetta, Elizabeta Cavar

Using the highly localized current of electrons tunneling through a double barrier scanning tunneling microscope junction, we excite luminescence from a selected C60 mol. in the surface layer of fullerene nanocrystals grown on an ultrathin NaCl film on Au( ...

2005

Preparation of stable AsBr4+ and I2As-PI3+ salts. Why didn't we succeed to prepare AsI4+ and As2X5+? A combined experimental and theoretical study

In analogy to the authors' successful PX2+ insertion reactions, an AsX2+ insertion route was explored to obtain new arsenic halogen cations. Two new salts were prepd.: AsBr4+[Al(OR)4]-, starting from AsBr3, Br2 and Ag[Al(OR)4], and I2As-PI3+[Al(OR)]4 from ...

2005